Qingzhong Hu

Lensfield Road, CB2 1EW
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 27 publications

Accelerated skin wound healing by selective 11β-Hydroxylase (CYP11B1) inhibitors.

Accelerated skin wound healing by selective 11β-Hydroxylase (CYP11B1) inhibitors.

Journal: European journal of medicinal chemistry

Published: September 13, 2017

Drifting of heme-coordinating group in imidazolylmethylxanthones leading to improved selective inhibition of CYP11B1.

Drifting of heme-coordinating group in imidazolylmethylxanthones leading to improved selective inhibition of CYP11B1.

Journal: European journal of medicinal chemistry

Published: June 15, 2017

Lead Optimization Generates CYP11B1 Inhibitors of Pyridylmethyl Isoxazole Type with Improved Pharmacological Profile for the Treatment of Cushing's Disease.

Lead Optimization Generates CYP11B1 Inhibitors of Pyridylmethyl Isoxazole Type with Improved Pharmacological Profile for the Treatment of Cushing's Disease.

Journal: Journal of medicinal chemistry

Published: June 02, 2017

Therapeutic compounds for Cushing's syndrome: a patent review (2012-2016).

Therapeutic compounds for Cushing's syndrome: a patent review (2012-2016).

Journal: Expert opinion on therapeutic patents

Published: July 26, 2016

Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis.

Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis.

Journal: Biochemical and biophysical research communications

Published: June 26, 2016

Exploiting the Chromone Scaffold for the Development of Inhibitors of Corticosteroid Biosynthesis.

Exploiting the Chromone Scaffold for the Development of Inhibitors of Corticosteroid Biosynthesis.

Journal: Journal of medicinal chemistry

Published: March 04, 2016

Targeting Steroidogenic Cytochromes P450 (CYPs) with 6-Substituted 1-Imidazolylmethylxanthones.

Targeting Steroidogenic Cytochromes P450 (CYPs) with 6-Substituted 1-Imidazolylmethylxanthones.

Journal: ChemMedChem

Published: February 04, 2016

Novel pyridyl substituted 4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines as potent and selective aldosterone synthase inhibitors with improved in vitro metabolic stability.

Novel pyridyl substituted 4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines as potent and selective aldosterone synthase inhibitors with improved in vitro metabolic stability.

Journal: Journal of medicinal chemistry

Published: February 26, 2015

Discovery of Triazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.

Discovery of Triazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.

Journal: ACS medicinal chemistry letters

Published: January 29, 2015

Identification of 4-(4-nitro-2-phenethoxyphenyl)pyridine as a promising new lead for discovering inhibitors of both human and rat 11β-Hydroxylase.

Identification of 4-(4-nitro-2-phenethoxyphenyl)pyridine as a promising new lead for discovering inhibitors of both human and rat 11β-Hydroxylase.

Journal: European journal of medicinal chemistry

Published: January 28, 2015

Heteroatom insertion into 3,4-dihydro-1H-quinolin-2-ones leads to potent and selective inhibitors of human and rat aldosterone synthase.

Heteroatom insertion into 3,4-dihydro-1H-quinolin-2-ones leads to potent and selective inhibitors of human and rat aldosterone synthase.

Journal: European journal of medicinal chemistry

Published: October 29, 2014

Potent 11β-hydroxylase inhibitors with inverse metabolic stability in human plasma and hepatic S9 fractions to promote wound healing.

Potent 11β-hydroxylase inhibitors with inverse metabolic stability in human plasma and hepatic S9 fractions to promote wound healing.

Journal: Journal of medicinal chemistry

Published: September 02, 2014

Showing 1-12 of 27

Last Updated: 09/26/2026