Qingzhong N. Jia

Shijiazhuang, 050017, China

Last Updated: 09/26/2026

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Found 36 publications

Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket.

Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket.

Journal: Journal of medicinal chemistry

Published: February 19, 2026

Design, synthesis, and biological evaluation of selective HDAC6 inhibitors featuring an N-benzyl-2-(aryl/heteroaryl)acetamide cap.

Design, synthesis, and biological evaluation of selective HDAC6 inhibitors featuring an N-benzyl-2-(aryl/heteroaryl)acetamide cap.

Journal: Bioorganic chemistry

Published: January 09, 2026

A-type potassium channels in pain signaling: Fundamental mechanisms and pathophysiological roles.

A-type potassium channels in pain signaling: Fundamental mechanisms and pathophysiological roles.

Journal: Pharmacology & therapeutics

Published: December 29, 2025

Integrated pharmacokinetic properties, tissue distribution and metabolism of multiple active constituents in DBD for the treatment of GEM-induced myelosuppression.

Integrated pharmacokinetic properties, tissue distribution and metabolism of multiple active constituents in DBD for the treatment of GEM-induced myelosuppression.

Journal: Journal of ethnopharmacology

Published: November 09, 2025

Synergistic antiarrhythmic mechanism of INa-L and RyR2 blockade: normalization of pathological calcium cycling and CaMKII signaling.

Synergistic antiarrhythmic mechanism of INa-L and RyR2 blockade: normalization of pathological calcium cycling and CaMKII signaling.

Journal: Journal of translational medicine

Published: October 08, 2025

RadioPharm: the database of radiopharmaceuticals.

RadioPharm: the database of radiopharmaceuticals.

Journal: Nucleic acids research

Published: August 09, 2025

The Kv4.3 channel on c-low threshold mechanoreceptors in DRG is a key mediator transforming tactile stimuli into nociceptive signals in chemotherapy-induced neuropathy.

The Kv4.3 channel on c-low threshold mechanoreceptors in DRG is a key mediator transforming tactile stimuli into nociceptive signals in chemotherapy-induced neuropathy.

Journal: Acta pharmaceutica Sinica. B

Published: June 05, 2025

Site-Selective Electrophilic Trifluoromethylthiolation for the Synthesis of C5- or C7-SCF3-Substituted Indolines.

Site-Selective Electrophilic Trifluoromethylthiolation for the Synthesis of C5- or C7-SCF3-Substituted Indolines.

Journal: Organic letters

Published: December 23, 2024

Discovery of selective HDAC6 inhibitors driven by artificial intelligence and molecular dynamics simulation approaches.

Discovery of selective HDAC6 inhibitors driven by artificial intelligence and molecular dynamics simulation approaches.

Journal: Journal of pharmaceutical analysis

Published: November 04, 2024

PDCdb: the biological activity and pharmaceutical information of peptide-drug conjugate (PDC).

PDCdb: the biological activity and pharmaceutical information of peptide-drug conjugate (PDC).

Journal: Nucleic acids research

Published: August 08, 2024

A Novel Compound QO-83 Alleviates Acute and Chronic Epileptic Seizures in Rodents by Modulating KV7 Channel Activity.

A Novel Compound QO-83 Alleviates Acute and Chronic Epileptic Seizures in Rodents by Modulating KV7 Channel Activity.

Journal: CNS neuroscience & therapeutics

Published: August 01, 2024

Discovery of Potent Selective HDAC6 Inhibitors with 5-Phenyl-1H-indole Fragment: Virtual Screening, Rational Design, and Biological Evaluation.

Discovery of Potent Selective HDAC6 Inhibitors with 5-Phenyl-1H-indole Fragment: Virtual Screening, Rational Design, and Biological Evaluation.

Journal: Journal of chemical information and modeling

Published: July 23, 2024

Showing 1-12 of 36

Last Updated: 09/26/2026