Qinlong F. Xu
Hefei, 230088, China
Last Updated: 09/26/2026
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Found 13 publications
Discovery of Highly Potent Phthalazinone Derivatives as PARP14 Inhibitors: From Structure-Based Virtual Screening to In Vivo Pharmacodynamic Activity.
Journal: Journal of medicinal chemistry
Published: April 20, 2026
Discovery of a spirocyclic influenza RNA-dependent RNA polymerase inhibitor.
Journal: Bioorganic chemistry
Published: August 14, 2025
Novel 3-n-butylphthalide derivatives as potent multi-functional anti-IS agents with BBB protective function.
Journal: Bioorganic chemistry
Published: August 13, 2025
Successive structural optimization of Ziritaxestat culminates in the discovery of orally bioavailable and in vivo potent imidazothiadiazole derivative for treating ATX-driven diseases.
Journal: European journal of medicinal chemistry
Published: April 06, 2025
Preclinical pharmacokinetic investigation of the bioavailability and skin distribution of HY-072808 ointment, a novel drug candidate for the treatment of atopic dermatitis, in minipigs by a newly LC-MS/MS method.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: March 19, 2024
Design, Synthesis, and Biological Evaluation of Pierardine Derivatives as Novel Brain-Penetrant and In Vivo Potent NMDAR-GluN2B Antagonists for Ischemic Stroke Treatment.
Journal: Journal of medicinal chemistry
Published: February 27, 2024
Discovery of the novel and potent histamine H1 receptor antagonists for treatment of allergic diseases.
Journal: European journal of medicinal chemistry
Published: November 23, 2023
Synthesis and biological evaluation of N-(benzene sulfonyl)acetamide derivatives as anti-inflammatory and analgesic agents with COX-2/5-LOX/TRPV1 multifunctional inhibitory activity.
Journal: Bioorganic & medicinal chemistry letters
Published: October 20, 2022
Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.
Journal: European journal of medicinal chemistry
Published: November 23, 2020
An elastic-net penalized expectile regression with applications.
Journal: Journal of applied statistics
Published: June 30, 2020
Design, synthesis and biological evaluation of novel desloratadine derivatives with anti-inflammatory and H1 antagonize activities.
Journal: Bioorganic & medicinal chemistry letters
Published: July 24, 2019
Design, synthesis chalcone derivatives as AdipoR agonist for type 2 diabetes.
Journal: Chemical biology & drug design
Published: July 13, 2017
Last Updated: 09/26/2026