Raafat A. Awady-El

University City Road, Sharjah 27272
Sharjah, SH, United Arab Emirates

Last Updated: 09/26/2026

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Found 78 publications

Pharmacological inhibition of CBP sensitizes breast cancer to DNA-damaging agents by compromising DNA repair and cell cycle pathways.

Pharmacological inhibition of CBP sensitizes breast cancer to DNA-damaging agents by compromising DNA repair and cell cycle pathways.

Journal: Translational research : the journal of laboratory and clinical medicine

Published: June 11, 2026

Harnessing DNA minor groove binding for cancer therapy: An overview.

Harnessing DNA minor groove binding for cancer therapy: An overview.

Journal: European journal of medicinal chemistry

Published: April 28, 2026

Structural and molecular insights into Helicobacter pylori CagA-SHP2 complex: From pathogenic signaling to targeted therapeutic opportunities in gastric cancer.

Structural and molecular insights into Helicobacter pylori CagA-SHP2 complex: From pathogenic signaling to targeted therapeutic opportunities in gastric cancer.

Journal: Microbiological research

Published: March 17, 2026

Estrogen /progesterone receptor-gasdermin E axis links hormone signalling to pyroptotic cell death, anti-tumour immunity and response to chemotherapy in breast cancer cells.

Estrogen /progesterone receptor-gasdermin E axis links hormone signalling to pyroptotic cell death, anti-tumour immunity and response to chemotherapy in breast cancer cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: March 11, 2026

Exploring the Impact of Two DNA Minor Groove Binder Compounds on HCT-116 Cells: A Comprehensive Multiomics Analysis Using Mass Spectrometry.

Exploring the Impact of Two DNA Minor Groove Binder Compounds on HCT-116 Cells: A Comprehensive Multiomics Analysis Using Mass Spectrometry.

Journal: Journal of proteome research

Published: March 06, 2026

Exploring the Impact of Carboxylic Groups on the Anti-Proliferative Activity of 5-Aminosalicylic-4-Thiazolinone Hybrids: Design, Synthesis, Biological Evaluation, and ADME Study.

Exploring the Impact of Carboxylic Groups on the Anti-Proliferative Activity of 5-Aminosalicylic-4-Thiazolinone Hybrids: Design, Synthesis, Biological Evaluation, and ADME Study.

Journal: Chemistry & biodiversity

Published: November 03, 2025

Nature-inspired chalcone-functionalized paracetamol derivatives as potential anticancer leads: synthesis, biological evaluation, apoptotic mechanisms, and in silico docking studies.

Nature-inspired chalcone-functionalized paracetamol derivatives as potential anticancer leads: synthesis, biological evaluation, apoptotic mechanisms, and in silico docking studies.

Journal: Bioorganic & medicinal chemistry letters

Published: October 23, 2025

Opposing outcomes of short- and long-term epigenetic therapy in breast cancer: Implications for chemotherapy response.

Opposing outcomes of short- and long-term epigenetic therapy in breast cancer: Implications for chemotherapy response.

Journal: Biochemical pharmacology

Published: September 30, 2025

Untargeted Multiomics of LNCaP Cell Line Treated with a Novel DNA Minor Groove Binder and/or Doxorubicin Using Mass Spectrometry.

Untargeted Multiomics of LNCaP Cell Line Treated with a Novel DNA Minor Groove Binder and/or Doxorubicin Using Mass Spectrometry.

Journal: Journal of proteome research

Published: September 04, 2025

Design, Synthesis, and Anticancer Evaluation of Novel MGBs with Alkyne-Linked Thiazole Moieties.

Design, Synthesis, and Anticancer Evaluation of Novel MGBs with Alkyne-Linked Thiazole Moieties.

Journal: Journal of medicinal chemistry

Published: July 10, 2025

Further insights into the multitarget anticancer activity of tetrahydrocarbazole-1-amine/5-arylidene-4-thiazolinone based hybrids.

Further insights into the multitarget anticancer activity of tetrahydrocarbazole-1-amine/5-arylidene-4-thiazolinone based hybrids.

Journal: Bioorganic chemistry

Published: June 12, 2025

LncRNAs signatures in gynecological cancers: ovarian and endometrial cancers.

LncRNAs signatures in gynecological cancers: ovarian and endometrial cancers.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Published: May 09, 2025

Showing 1-12 of 78

Last Updated: 09/26/2026