Rachel E. Piddock

Norwich Research Park
Norwich, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 13 publications

Biallelic TET2 mutations confer sensitivity to 5'-azacitidine in acute myeloid leukemia.

Biallelic TET2 mutations confer sensitivity to 5'-azacitidine in acute myeloid leukemia.

Journal: JCI insight
Published: April 13, 2021

Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia.

Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia.

Journal: Nature communications
Published: October 10, 2019

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.

Journal: Blood
Published: April 14, 2018

CD38-Driven Mitochondrial Trafficking Promotes Bioenergetic Plasticity in Multiple Myeloma.

CD38-Driven Mitochondrial Trafficking Promotes Bioenergetic Plasticity in Multiple Myeloma.

Journal: Cancer research
Published: March 12, 2018

PGC-1α driven mitochondrial biogenesis in stromal cells underpins mitochondrial trafficking to leukemic blasts.

PGC-1α driven mitochondrial biogenesis in stromal cells underpins mitochondrial trafficking to leukemic blasts.

Journal: Leukemia
Published: March 03, 2018

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC.

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC.

Journal: Journal of hematology & oncology
Published: February 21, 2018

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia.

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia.

Journal: Oncogene
Published: August 03, 2017

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts.

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts.

Journal: Blood
Published: March 10, 2017

The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma.

The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma.

Journal: Cancers
Published: January 31, 2017

PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment.

PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment.

Journal: Blood cancer journal
Published: January 16, 2017

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment.

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment.

Journal: Blood
Published: August 18, 2016

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection.

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection.

Journal: Oncotarget
Published: October 06, 2015
Showing 1-12 of 13

Last Updated: 09/26/2026