Radim Osicka

Prague, PR, Czech Republic

Last Updated: 09/26/2026

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Found 58 publications

Calcium-loaded acylated segment controls membrane penetration capacity of repeats-in-toxin cytolysins.

Calcium-loaded acylated segment controls membrane penetration capacity of repeats-in-toxin cytolysins.

Journal: The Journal of biological chemistry

Published: January 20, 2026

Kingella kingae cytotoxin RtxA induces an innate immune response in oral epithelial cells.

Kingella kingae cytotoxin RtxA induces an innate immune response in oral epithelial cells.

Journal: Current research in microbial sciences

Published: July 16, 2025

Intranasal application of a bifunctional pertactin-RTX fusion antigen elicits protection of mouse airway mucosa against Bordetella pertussis colonization.

Intranasal application of a bifunctional pertactin-RTX fusion antigen elicits protection of mouse airway mucosa against Bordetella pertussis colonization.

Journal: mSphere

Published: March 31, 2025

Structural and functional significance of two conserved lysine residues in acylated sites of Kingella kingae RtxA cytotoxin.

Structural and functional significance of two conserved lysine residues in acylated sites of Kingella kingae RtxA cytotoxin.

Journal: Biochimie

Published: November 08, 2024

Acyl chains stabilize the acylated domain and determine the receptor-mediated interaction of the Bordetella adenylate cyclase toxin with cell membrane.

Acyl chains stabilize the acylated domain and determine the receptor-mediated interaction of the Bordetella adenylate cyclase toxin with cell membrane.

Journal: The Journal of biological chemistry

Published: October 25, 2024

Two pairs of back-to-back α-helices of Kingella kingae RtxA toxin are crucial for the formation of a membrane pore.

Two pairs of back-to-back α-helices of Kingella kingae RtxA toxin are crucial for the formation of a membrane pore.

Journal: International journal of biological macromolecules

Published: September 27, 2024

Human IL-22 receptor-targeted small protein antagonist suppress murine DSS-induced colitis.

Human IL-22 receptor-targeted small protein antagonist suppress murine DSS-induced colitis.

Journal: Cell communication and signaling : CCS

Published: February 27, 2024

Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.

Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.

Journal: Biochimica et biophysica acta. Biomembranes

Published: February 01, 2024

Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells.

Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells.

Journal: Cell communication and signaling : CCS

Published: December 13, 2023

A conserved tryptophan in the acylated segment of RTX toxins controls their β2 integrin-independent cell penetration.

A conserved tryptophan in the acylated segment of RTX toxins controls their β2 integrin-independent cell penetration.

Journal: The Journal of biological chemistry

Published: April 19, 2023

Kingella kingae RtxA toxin interacts with sialylated gangliosides.

Kingella kingae RtxA toxin interacts with sialylated gangliosides.

Journal: Microbial pathogenesis

Published: April 14, 2023

Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions.

Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions.

Journal: Scientific reports

Published: November 01, 2022

Showing 1-12 of 58

Last Updated: 09/26/2026