Rafael C. Chelucci

Sao Carlos, SP, Brazil

Last Updated: 09/26/2026

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Found 22 publications

Identification of a Benzenesulfonylpiperazine Derivative With In Vivo Efficacy Against Visceral Leishmaniasis.

Identification of a Benzenesulfonylpiperazine Derivative With In Vivo Efficacy Against Visceral Leishmaniasis.

Journal: Chemical biology & drug design

Published: April 10, 2026

Multiscale-Aware Graph Embedding Approach Uncovers LC-61, a Potent Anti-Leishmania infantum Compound.

Multiscale-Aware Graph Embedding Approach Uncovers LC-61, a Potent Anti-Leishmania infantum Compound.

Journal: Journal of chemical information and modeling

Published: March 17, 2026

Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy.

Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy.

Journal: European journal of medicinal chemistry

Published: March 09, 2026

Hit-To-Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy of Optimized Compounds.

Hit-To-Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy of Optimized Compounds.

Journal: ChemMedChem

Published: January 31, 2026

Design and Synthesis of Boronic Chalcones with Dual Anticancer and Anti-Inflammatory Activity.

Design and Synthesis of Boronic Chalcones with Dual Anticancer and Anti-Inflammatory Activity.

Journal: Molecules (Basel, Switzerland)

Published: June 11, 2025

Discovery and Early Optimization of 1H-Indole-2-carboxamides with Anti-Trypanosoma cruzi Activity.

Discovery and Early Optimization of 1H-Indole-2-carboxamides with Anti-Trypanosoma cruzi Activity.

Journal: Journal of medicinal chemistry

Published: March 31, 2025

Isoindoline-1,3-dione Derivatives as Prototypes for Anticonvulsant Drug Discovery.

Isoindoline-1,3-dione Derivatives as Prototypes for Anticonvulsant Drug Discovery.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))

Published: August 01, 2024

Evaluation and discovery of novel benzothiazole derivatives as promising hits against Leishmania infantum.

Evaluation and discovery of novel benzothiazole derivatives as promising hits against Leishmania infantum.

Journal: Chemical biology & drug design

Published: January 20, 2024

Structure-activity relationships of novel N-imidazoylpiperazines with potent anti-Trypanosoma cruzi activity.

Structure-activity relationships of novel N-imidazoylpiperazines with potent anti-Trypanosoma cruzi activity.

Journal: Future medicinal chemistry

Published: January 09, 2024

Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease.

Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease.

Journal: European journal of medicinal chemistry

Published: September 25, 2022

Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery.

Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery.

Journal: PloS one

Published: June 10, 2022

Hit-to-lead optimization of a benzene sulfonamide series for potential antileishmanial agents.

Hit-to-lead optimization of a benzene sulfonamide series for potential antileishmanial agents.

Journal: RSC medicinal chemistry

Published: June 04, 2021

Showing 1-12 of 22

Last Updated: 09/26/2026