Rafael L. Portella

Ribeirao Preto, SP, Brazil

Last Updated: 09/26/2026

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Found 12 publications

Orally administered sodium nitrite prevents the increased α-1 adrenergic vasoconstriction induced by hypertension and promotes the S-nitrosylation of calcium/calmodulin-dependent protein kinase II.

Orally administered sodium nitrite prevents the increased α-1 adrenergic vasoconstriction induced by hypertension and promotes the S-nitrosylation of calcium/calmodulin-dependent protein kinase II.

Journal: Biochemical pharmacology

Published: February 13, 2023

Nitrite and tempol combination promotes synergic effects and alleviates right ventricular wall stress during acute pulmonary thromboembolism.

Nitrite and tempol combination promotes synergic effects and alleviates right ventricular wall stress during acute pulmonary thromboembolism.

Journal: Nitric oxide : biology and chemistry

Published: February 12, 2021

Antioxidant tempol modulates the increases in tissue nitric oxide metabolites concentrations after oral nitrite administration.

Antioxidant tempol modulates the increases in tissue nitric oxide metabolites concentrations after oral nitrite administration.

Journal: Chemico-biological interactions

Published: December 21, 2020

Sodium nitrite improves hypertension-induced myocardial dysfunction by mechanisms involving cardiac S-nitrosylation.

Sodium nitrite improves hypertension-induced myocardial dysfunction by mechanisms involving cardiac S-nitrosylation.

Journal: Journal of molecular and cellular cardiology

Published: January 27, 2019

Effect of Physical Exercise on Endometriosis Experimentally Induced in Rats.

Effect of Physical Exercise on Endometriosis Experimentally Induced in Rats.

Journal: Reproductive sciences (Thousand Oaks, Calif.)

Published: September 21, 2018

Nitrate decreases xanthine oxidoreductase-mediated nitrite reductase activity and attenuates vascular and blood pressure responses to nitrite.

Nitrate decreases xanthine oxidoreductase-mediated nitrite reductase activity and attenuates vascular and blood pressure responses to nitrite.

Journal: Redox biology

Published: December 14, 2016

Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect.

Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect.

Journal: Free radical biology & medicine

Published: July 26, 2016

Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction.

Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction.

Journal: Redox biology

Published: July 04, 2016

Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension.

Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension.

Journal: Free radical biology & medicine

Published: February 25, 2015

Vascular xanthine oxidoreductase contributes to the antihypertensive effects of sodium nitrite in L-NAME hypertension.

Vascular xanthine oxidoreductase contributes to the antihypertensive effects of sodium nitrite in L-NAME hypertension.

Journal: Naunyn-Schmiedeberg's archives of pharmacology

Published: October 18, 2013

The antioxidant tempol decreases acute pulmonary thromboembolism-induced hemolysis and nitric oxide consumption.

The antioxidant tempol decreases acute pulmonary thromboembolism-induced hemolysis and nitric oxide consumption.

Journal: Thrombosis research

Published: July 24, 2013

Antihypertensive effects of inducible nitric oxide synthase inhibition in experimental pre-eclampsia.

Antihypertensive effects of inducible nitric oxide synthase inhibition in experimental pre-eclampsia.

Journal: Journal of cellular and molecular medicine

Published: April 12, 2013

Showing 1-12 of 12

Last Updated: 09/26/2026