Rafaela S. Ferreira

6627, Antônio Carlos Avenue
Belo Horizonte, MG 31270901, Brazil

Last Updated: 09/26/2026

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Found 96 publications

Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy.

Discovery of an efficacious 2-ethyl-4-phenylthiazole derivative against acute Chagas disease via multiparametric hit-to-lead optimization and in vivo efficacy.

Journal: European journal of medicinal chemistry
Published: March 09, 2026

Neuwlectin, a novel C-type lectin from Bothrops neuwiedi venom, inhibits platelet aggregation induced by cancer cells and angiogenesis.

Neuwlectin, a novel C-type lectin from Bothrops neuwiedi venom, inhibits platelet aggregation induced by cancer cells and angiogenesis.

Journal: Biochimie
Published: January 30, 2026

Neuwlectin, a novel C-type lectin from Bothrops neuwiedi venom, inhibits platelet aggregation induced by cancer cells and angiogenesis.

Neuwlectin, a novel C-type lectin from Bothrops neuwiedi venom, inhibits platelet aggregation induced by cancer cells and angiogenesis.

Journal: Biochimie
Published: January 30, 2026

5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazine-based thiosemicarbazones as anti-Trypanosoma cruzi agents.

5,6,7,8-Tetrahydroimidazo[1,2-a]pyrazine-based thiosemicarbazones as anti-Trypanosoma cruzi agents.

Journal: Bioorganic & medicinal chemistry
Published: January 24, 2026

Structure-Based Discovery of Non-Covalent Triazole-Based Cruzipain Inhibitors with Improved Bioactivity Translation.

Structure-Based Discovery of Non-Covalent Triazole-Based Cruzipain Inhibitors with Improved Bioactivity Translation.

Journal: Journal of chemical information and modeling
Published: November 08, 2025

Acetylation-mediated fluconazole inactivation: A novel antifungal resistance mechanism.

Acetylation-mediated fluconazole inactivation: A novel antifungal resistance mechanism.

Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Published: November 06, 2025

Thiosulfonate-Based Targeted Covalent Cruzipain Inhibitors with Enhanced Bioactivity Translation for Antichagasic Therapy.

Thiosulfonate-Based Targeted Covalent Cruzipain Inhibitors with Enhanced Bioactivity Translation for Antichagasic Therapy.

Journal: ACS medicinal chemistry letters
Published: December 28, 2024

Zileuton, a 5-Lypoxigenase Inhibitor, is Antiparasitic and Prevents Inflammation in the Chronic Stage of Heart Chagas Disease.

Zileuton, a 5-Lypoxigenase Inhibitor, is Antiparasitic and Prevents Inflammation in the Chronic Stage of Heart Chagas Disease.

Journal: ACS infectious diseases
Published: November 28, 2024

Discovery of a Potent Triazole-Based Reversible Targeted Covalent Inhibitor of Cruzipain.

Discovery of a Potent Triazole-Based Reversible Targeted Covalent Inhibitor of Cruzipain.

Journal: ACS medicinal chemistry letters
Published: September 21, 2024

Ouratein D, a Biflavanone From Ouratea spectabilis, Alleviates Betacoronavirus Infection by Mitigating Inflammation, Lung Damage and Viral Replication.

Ouratein D, a Biflavanone From Ouratea spectabilis, Alleviates Betacoronavirus Infection by Mitigating Inflammation, Lung Damage and Viral Replication.

Journal: Phytotherapy research : PTR
Published: August 19, 2024

Investigation of the activity of 4-aminoquinolines as cysteine protease inhibitors with application in the treatment of Chagas disease.

Investigation of the activity of 4-aminoquinolines as cysteine protease inhibitors with application in the treatment of Chagas disease.

Journal: Memorias do Instituto Oswaldo Cruz
Published: July 17, 2024

Structure-Aided Computational Design of Triazole-Based Targeted Covalent Inhibitors of Cruzipain.

Structure-Aided Computational Design of Triazole-Based Targeted Covalent Inhibitors of Cruzipain.

Journal: Molecules (Basel, Switzerland)
Published: July 03, 2024
Showing 1-12 of 96

Last Updated: 09/26/2026