Ralf Ficner

Goettingen, NI, Germany

Last Updated: 09/26/2026

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Found 112 publications

New structures of human formylglycine-generating enzyme reveal features important for catalysis, disease and structure-based drug design.

New structures of human formylglycine-generating enzyme reveal features important for catalysis, disease and structure-based drug design.

Journal: Journal of molecular biology

Published: February 18, 2026

Alphafold 3-guided insights into the Importinβ: Importin7 heterodimer interaction and its binding to histone H1.

Alphafold 3-guided insights into the Importinβ: Importin7 heterodimer interaction and its binding to histone H1.

Journal: Structure (London, England : 1993)

Published: August 27, 2025

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2.

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2.

Journal: RNA (New York, N.Y.)

Published: June 23, 2025

Nucleotide-bound crystal structures of the SARS-CoV-2 helicase NSP13.

Nucleotide-bound crystal structures of the SARS-CoV-2 helicase NSP13.

Journal: Acta crystallographica. Section F, Structural biology communications

Published: February 14, 2025

The Aspergillus nidulans velvet domain containing transcription factor VeA is shuttled from cytoplasm into nucleus during vegetative growth and stays there for sexual development, but has to return into cytoplasm for asexual development.

The Aspergillus nidulans velvet domain containing transcription factor VeA is shuttled from cytoplasm into nucleus during vegetative growth and stays there for sexual development, but has to return into cytoplasm for asexual development.

Journal: PLoS genetics

Published: February 12, 2025

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors.

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors.

Journal: Acta crystallographica. Section D, Structural biology

Published: February 07, 2025

RNA-modification by Base Exchange: Structure, Function and Application of tRNA-guanine Transglycosylases.

RNA-modification by Base Exchange: Structure, Function and Application of tRNA-guanine Transglycosylases.

Journal: Journal of molecular biology

Published: November 18, 2024

Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry.

Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry.

Journal: bioRxiv : the preprint server for biology

Published: September 11, 2024

Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry.

Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry.

Journal: Nucleic acids research

Published: July 30, 2024

Crystallographic fragment screen of the c-di-AMP-synthesizing enzyme CdaA from Bacillus subtilis.

Crystallographic fragment screen of the c-di-AMP-synthesizing enzyme CdaA from Bacillus subtilis.

Journal: Acta crystallographica. Section F, Structural biology communications

Published: May 24, 2024

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2.

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2.

Journal: bioRxiv : the preprint server for biology

Published: May 07, 2024

A small step towards an important goal: fragment screen of the c-di-AMP-synthesizing enzyme CdaA.

A small step towards an important goal: fragment screen of the c-di-AMP-synthesizing enzyme CdaA.

Journal: Acta crystallographica. Section D, Structural biology

Published: February 22, 2024

Showing 1-12 of 112

Last Updated: 09/26/2026