Ralph Imhof
Zurich, ZH 8057, Switzerland
Last Updated: 09/26/2026
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Found 20 publications
Time-Resolved Single-Molecule FRET Reveals Length-Dependent Nucleosome Decompaction by Poly(ADP-ribose).
Journal: bioRxiv : the preprint server for biology
Published: April 29, 2026
Identification of CNOT1-CCR4-NOT as a suppressor of 53BP1-p53-p21 signaling.
Journal: Cell reports
Published: November 26, 2024
Multigenerational cell tracking of DNA replication and heritable DNA damage.
Journal: Nature
Published: April 04, 2024
Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres.
Journal: Nature structural & molecular biology
Published: January 31, 2022
RPA shields inherited DNA lesions for post-mitotic DNA synthesis.
Journal: Nature communications
Published: May 20, 2020
Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins.
Journal: Nature communications
Published: January 20, 2020
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.
Journal: Nature communications
Published: October 28, 2019
The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency.
Journal: Cell reports
Published: October 17, 2019
Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions.
Journal: The Journal of cell biology
Published: February 14, 2019
Phase separation of 53BP1 determines liquid-like behavior of DNA repair compartments.
Journal: The EMBO journal
Published: December 14, 2018
Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability.
Journal: Molecular cell
Published: April 16, 2018
Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance.
Journal: Nature communications
Published: October 12, 2017
Last Updated: 09/26/2026