Randolph P. Matthews
Pediatric Gastroenterology
3401 Civic Center Blvd
Philadelphia, PA 19104
Philadelphia, PA 19104
Last Updated: 09/26/2026
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Found 29 publications
Antiretroviral Activity, Pharmacokinetics, and Safety of MK-8527, an Oral Nucleoside Reverse Transcriptase Translocation Inhibitor, in Adults With HIV-1 Who Had Not Previously Taken Antiretroviral Agents: Results From 2 Open-Label, Phase 1 Studies.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Published: August 20, 2025
Pharmacokinetics of islatravir in participants with moderate hepatic impairment.
Journal: Antimicrobial agents and chemotherapy
Published: March 05, 2025
Safety and Pharmacokinetics of MK-8527 in Adults Without HIV.
Journal: Clinical and translational science
Published: February 11, 2025
Nonclinical and clinical characterization of the absorption, metabolism, and excretion of islatravir.
Journal: Antimicrobial agents and chemotherapy
Published: January 14, 2025
Pharmacokinetics of Atorvastatin and Metformin after Coadministration with Islatravir in Healthy Adults.
Journal: Journal of clinical pharmacology
Published: September 18, 2024
Intracellular islatravir-triphosphate half-life supports extended dosing intervals.
Journal: Antimicrobial agents and chemotherapy
Published: August 06, 2024
Thorough QT/QTc study to evaluate the effect of a single supratherapeutic dose of islatravir on QTc interval prolongation in healthy adults.
Journal: Antimicrobial agents and chemotherapy
Published: July 02, 2024
A Phase 1 Study to Evaluate the Pharmacokinetic Drug-Drug Interaction Between Islatravir and Methadone in Participants on Stable Methadone Therapy.
Journal: Clinical pharmacology in drug development
Published: May 17, 2024
Considerations for Cell and Gene Therapy Programs Entering the Clinical Space.
Journal: Clinical pharmacology and therapeutics
Published: April 13, 2023
Safety and Pharmacokinetics of Islatravir in Individuals with Severe Renal Insufficiency.
Journal: Antimicrobial agents and chemotherapy
Published: November 08, 2022
A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial of Radiopaque Islatravir-Eluting Subdermal Implants for Pre-exposure Prophylaxis Against HIV-1 Infection.
Journal: Journal of acquired immune deficiency syndromes (1999)
Published: May 24, 2022
Incorporating protein precipitation to resolve hybrid IP-LC-MS assay interference for ultrasensitive quantification of intact therapeutic insulin dimer in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis
Published: September 19, 2021
Last Updated: 09/26/2026