Ratan V. Bhat

AstraZeneca R&D
Goeteborg, O, Sweden

Last Updated: 09/26/2026

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Found 11 publications

MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.

MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: April 03, 2024

Unbiased kidney-centric molecular categorization of chronic kidney disease as a step towards precision medicine.

Unbiased kidney-centric molecular categorization of chronic kidney disease as a step towards precision medicine.

Journal: Kidney international

Published: September 13, 2023

Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes.

Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes.

Journal: Cardiovascular research

Published: May 20, 2020

SUMO-specific protease 2 mediates leptin-induced fatty acid oxidation in skeletal muscle.

SUMO-specific protease 2 mediates leptin-induced fatty acid oxidation in skeletal muscle.

Journal: Metabolism: clinical and experimental

Published: January 10, 2019

Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes.

Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes.

Journal: International journal of cardiology

Published: June 29, 2018

The Conundrum of GSK3 Inhibitors: Is it the Dawn of a New Beginning?

The Conundrum of GSK3 Inhibitors: Is it the Dawn of a New Beginning?

Journal: Journal of Alzheimer's disease : JAD

Published: May 16, 2018

Association of Cardiomyopathy With MYBPC3 D389V and MYBPC3Δ25bpIntronic Deletion in South Asian Descendants.

Association of Cardiomyopathy With MYBPC3 D389V and MYBPC3Δ25bpIntronic Deletion in South Asian Descendants.

Journal: JAMA cardiology

Published: April 12, 2018

Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction.

Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction.

Journal: Journal of the American Heart Association

Published: June 15, 2017

Beyond amyloid: getting real about nonamyloid targets in Alzheimer's disease.

Beyond amyloid: getting real about nonamyloid targets in Alzheimer's disease.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: January 15, 2013

AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.

AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.

Journal: Journal of neurochemistry

Published: November 23, 2012

Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.

Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.

Journal: Journal of medicinal chemistry

Published: April 12, 2012

Showing 1-11 of 11

Last Updated: 09/26/2026