Raymond Hui

610 University Avenue, M5G 2M9
Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 18 publications

Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.

Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 27, 2019

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.

Journal: Nature communications

Published: June 22, 2018

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

Journal: ACS infectious diseases

Published: February 14, 2018

Inhibition of Calcium Dependent Protein Kinase 1 (CDPK1) by Pyrazolopyrimidine Analogs Decreases Establishment and Reoccurrence of Central Nervous System Disease by Toxoplasma gondii.

Inhibition of Calcium Dependent Protein Kinase 1 (CDPK1) by Pyrazolopyrimidine Analogs Decreases Establishment and Reoccurrence of Central Nervous System Disease by Toxoplasma gondii.

Journal: Journal of medicinal chemistry

Published: September 22, 2017

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

Journal: Nature communications

Published: February 20, 2017

Discovery and structure activity relationship of the first potent cryptosporidium FIKK kinase inhibitor.

Discovery and structure activity relationship of the first potent cryptosporidium FIKK kinase inhibitor.

Journal: Bioorganic & medicinal chemistry

Published: December 16, 2016

Discovery of a PCAF Bromodomain Chemical Probe.

Discovery of a PCAF Bromodomain Chemical Probe.

Journal: Angewandte Chemie (International ed. in English)

Published: November 05, 2016

Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

Journal: ACS infectious diseases

Published: July 06, 2016

Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling.

Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling.

Journal: The Journal of biological chemistry

Published: November 10, 2015

Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.

Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.

Journal: PloS one

Published: September 10, 2015

Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.

Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.

Journal: Trends in pharmacological sciences

Published: March 06, 2015

Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design.

Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design.

Journal: Biochimica et biophysica acta

Published: February 15, 2015

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Last Updated: 09/26/2026