Razan Sheta

Laval, QC G1V0A6, Canada

Last Updated: 09/26/2026

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Found 22 publications

Modeling Parkinson's pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity.

Modeling Parkinson's pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity.

Journal: Science advances
Published: July 10, 2026

WDR44 drives de novo α-synuclein aggregation at the lysosomal membrane and promotes neuronal dysfunction in Parkinson's Disease.

WDR44 drives de novo α-synuclein aggregation at the lysosomal membrane and promotes neuronal dysfunction in Parkinson's Disease.

Journal: bioRxiv : the preprint server for biology
Published: April 17, 2026

The emerging role of polo-like kinase 2 in Alzheimer's disease.

The emerging role of polo-like kinase 2 in Alzheimer's disease.

Journal: Experimental neurology
Published: August 31, 2025

Interplay between lipid droplets and alpha-synuclein: implication in Parkinson's disease pathogenesis.

Interplay between lipid droplets and alpha-synuclein: implication in Parkinson's disease pathogenesis.

Journal: Frontiers in molecular neuroscience
Published: August 06, 2025

Optogenetic-induced α-synuclein accumulation reveals early synaptic dysfunction in experimental models of Parkinson's disease.

Optogenetic-induced α-synuclein accumulation reveals early synaptic dysfunction in experimental models of Parkinson's disease.

Journal: NPJ Parkinson's disease
Published: July 23, 2025

Combining light-induced aggregation and biotin proximity labeling implicates endolysosomal proteins in early α-synuclein oligomerization.

Combining light-induced aggregation and biotin proximity labeling implicates endolysosomal proteins in early α-synuclein oligomerization.

Journal: iScience
Published: October 16, 2024

Behavioral analysis of motor and non-motor impairment in rodent models of Parkinson's disease.

Behavioral analysis of motor and non-motor impairment in rodent models of Parkinson's disease.

Journal: Frontiers in aging neuroscience
Published: July 15, 2024

Optogenetic-mediated induction and monitoring of α-synuclein aggregation in cellular models of Parkinson's disease.

Optogenetic-mediated induction and monitoring of α-synuclein aggregation in cellular models of Parkinson's disease.

Journal: STAR protocols
Published: August 10, 2023

Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons.

Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons.

Journal: STAR protocols
Published: March 24, 2023

Non-invasive systemic viral delivery of human alpha-synuclein mimics selective and progressive neuropathology of Parkinson's disease in rodent brains.

Non-invasive systemic viral delivery of human alpha-synuclein mimics selective and progressive neuropathology of Parkinson's disease in rodent brains.

Journal: Molecular neurodegeneration
Published: February 01, 2023

Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization.

Aggregation of alpha-synuclein disrupts mitochondrial metabolism and induce mitophagy via cardiolipin externalization.

Journal: Cell death & disease
Published: January 03, 2023

Inhibition of PLK2 activity affects APP and tau pathology and improves synaptic content in a sex-dependent manner in a 3xTg mouse model of Alzheimer's disease.

Inhibition of PLK2 activity affects APP and tau pathology and improves synaptic content in a sex-dependent manner in a 3xTg mouse model of Alzheimer's disease.

Journal: Neurobiology of disease
Published: March 13, 2022
Showing 1-12 of 22

Last Updated: 09/26/2026