Razq Hakem
Toronto, ON M5G1L7, Canada
Last Updated: 09/26/2026
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Found 16 publications
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.
Journal: The Journal of clinical investigation
Published: July 01, 2021
Modification of BRCA1-associated breast cancer risk by HMMR overexpression.
Journal: Nature communications
Published: May 20, 2021
The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.
Journal: Nature cell biology
Published: May 11, 2021
Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis.
Journal: EMBO molecular medicine
Published: January 09, 2021
Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand.
Journal: Oncogene
Published: December 03, 2020
Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Journal: Nature immunology
Published: December 11, 2018
The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils.
Journal: Science signaling
Published: September 06, 2018
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.
Journal: The Journal of clinical investigation
Published: February 07, 2018
The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.
Journal: Immunity
Published: September 24, 2015
Last Updated: 09/26/2026