Razqallah Hakem

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 35 publications

Adipocyte caspase-8 but not RIPK3 promotes adiposity.

Adipocyte caspase-8 but not RIPK3 promotes adiposity.

Journal: Cell death discovery

Published: December 09, 2025

Paradoxical oncogenic effects of hepatic Brca1 through modulating Bhmt.

Paradoxical oncogenic effects of hepatic Brca1 through modulating Bhmt.

Journal: Scientific reports

Published: August 20, 2025

PRMT1 inhibitor MS023 suppresses RNA splicing to sensitize small cell lung cancer to DNA damaging agents.

PRMT1 inhibitor MS023 suppresses RNA splicing to sensitize small cell lung cancer to DNA damaging agents.

Journal: Neoplasia (New York, N.Y.)

Published: November 29, 2024

Harnessing transcriptional regulation of alternative end-joining to predict cancer treatment.

Harnessing transcriptional regulation of alternative end-joining to predict cancer treatment.

Journal: NAR cancer

Published: October 17, 2024

CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer.

CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer.

Journal: Molecular cancer therapeutics

Published: September 27, 2024

Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells.

Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells.

Journal: STAR protocols

Published: May 09, 2024

DNA double-strand break-capturing nuclear envelope tubules drive DNA repair.

DNA double-strand break-capturing nuclear envelope tubules drive DNA repair.

Journal: Nature structural & molecular biology

Published: March 09, 2024

Nucleolar Pol II interactome reveals TBPL1, PAF1, and Pol I at intergenic rDNA drive rRNA biogenesis.

Nucleolar Pol II interactome reveals TBPL1, PAF1, and Pol I at intergenic rDNA drive rRNA biogenesis.

Journal: Nature communications

Published: November 23, 2023

In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.

In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.

Journal: Nature genetics

Published: November 10, 2023

A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity.

A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity.

Journal: iScience

Published: November 09, 2023

Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.

Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.

Journal: Cell reports

Published: October 26, 2023

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

Journal: Nucleic acids research

Published: May 09, 2023

Showing 1-12 of 35

Last Updated: 09/26/2026