Reece M. Hoffmann

Victoria, BC V8W2Y2, Canada

Last Updated: 09/26/2026

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Found 15 publications

A novel double-stranded DNA Badnavirus, prunus gummosis bark splitting virus infecting plum.

A novel double-stranded DNA Badnavirus, prunus gummosis bark splitting virus infecting plum.

Journal: Plant disease
Published: June 09, 2026

Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes.

Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes.

Journal: eLife
Published: February 11, 2022

Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.

Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.

Journal: Nature communications
Published: July 28, 2021

Probing Protein-Membrane Interactions and Dynamics Using Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS).

Probing Protein-Membrane Interactions and Dynamics Using Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS).

Journal: Methods in molecular biology (Clifton, N.J.)
Published: April 20, 2021

The middle lipin domain adopts a membrane-binding dimeric protein fold.

The middle lipin domain adopts a membrane-binding dimeric protein fold.

Journal: Nature communications
Published: March 16, 2021

Publisher Correction: Crystal structure of a lipin/Pah phosphatidic acid phosphatase.

Publisher Correction: Crystal structure of a lipin/Pah phosphatidic acid phosphatase.

Journal: Nature communications
Published: April 04, 2020

Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function.

Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function.

Journal: Structure (London, England : 1993)
Published: November 13, 2019

Crystal structure of a lipin/Pah phosphatidic acid phosphatase.

Crystal structure of a lipin/Pah phosphatidic acid phosphatase.

Journal: Nature communications
Published: November 03, 2019

(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase.

(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase.

Journal: Journal of medicinal chemistry
Published: June 28, 2019

Characterization of the c10orf76-PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication.

Characterization of the c10orf76-PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication.

Journal: EMBO reports
Published: May 09, 2019

The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme.

The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme.

Journal: The Journal of biological chemistry
Published: December 23, 2018

Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester.

Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester.

Journal: Journal of medicinal chemistry
Published: November 02, 2018
Showing 1-12 of 15

Last Updated: 09/26/2026