Regina De Beer

Amsterdam, NH 1105AZ, Netherlands

Last Updated: 09/26/2026

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Found 15 publications

The Sirt1 Activator SRT1720 Mitigates Human Monocyte Activation and Improves Outcome During Gram-Negative Pneumosepsis in Mice.

The Sirt1 Activator SRT1720 Mitigates Human Monocyte Activation and Improves Outcome During Gram-Negative Pneumosepsis in Mice.

Journal: International journal of molecular sciences

Published: August 11, 2025

Uncovering metabolic pathways in human alveolar macrophages in response to lipopolysaccharide.

Uncovering metabolic pathways in human alveolar macrophages in response to lipopolysaccharide.

Journal: Clinical and experimental immunology

Published: October 29, 2024

Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae.

Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae.

Journal: Journal of innate immunity

Published: July 23, 2021

Bruton's Tyrosine Kinase-Mediated Signaling in Myeloid Cells Is Required for Protective Innate Immunity During Pneumococcal Pneumonia.

Bruton's Tyrosine Kinase-Mediated Signaling in Myeloid Cells Is Required for Protective Innate Immunity During Pneumococcal Pneumonia.

Journal: Frontiers in immunology

Published: June 15, 2021

Caspase-11 contributes to pulmonary host defense against Klebsiella pneumoniae and local activation of coagulation.

Caspase-11 contributes to pulmonary host defense against Klebsiella pneumoniae and local activation of coagulation.

Journal: American journal of physiology. Lung cellular and molecular physiology

Published: May 14, 2020

Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model.

Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model.

Journal: Respiratory research

Published: May 03, 2019

Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis.

Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis.

Journal: Thrombosis and haemostasis

Published: March 16, 2019

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia.

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia.

Journal: Molecular medicine (Cambridge, Mass.)

Published: August 22, 2018

ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice.

ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice.

Journal: European journal of immunology

Published: June 06, 2016

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia.

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia.

Journal: Gut

Published: April 03, 2015

The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice.

Journal: PloS one

Published: September 15, 2014

Mast cells impair host defense during murine Streptococcus pneumoniae pneumonia.

Mast cells impair host defense during murine Streptococcus pneumoniae pneumonia.

Journal: The Journal of infectious diseases

Published: May 15, 2014

Showing 1-12 of 15

Last Updated: 09/26/2026