Reinhard Paschke

Ernst Grube Str. 40
Halle, NI 06120, Germany

Last Updated: 09/26/2026

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Found 25 publications

Combination of Betulinic Acid Fragments and Carbonic Anhydrase Inhibitors-A New Drug Targeting Approach.

Combination of Betulinic Acid Fragments and Carbonic Anhydrase Inhibitors-A New Drug Targeting Approach.

Journal: Pharmaceutics

Published: February 07, 2024

Potent drug delivery enhancement of betulinic acid and NVX-207 into equine skin in vitro - a comparison between a novel oxygen flow-assisted transdermal application device and microemulsion gels.

Potent drug delivery enhancement of betulinic acid and NVX-207 into equine skin in vitro - a comparison between a novel oxygen flow-assisted transdermal application device and microemulsion gels.

Journal: BMC veterinary research

Published: November 03, 2023

An Electrostatically-steered Conformational Selection Mechanism Promotes SARS-CoV-2 Spike Protein Variation.

An Electrostatically-steered Conformational Selection Mechanism Promotes SARS-CoV-2 Spike Protein Variation.

Journal: Journal of molecular biology

Published: January 18, 2022

Effects of Topically Applied Betulinic Acid and NVX-207 on Melanocytic Tumors in 18 Horses.

Effects of Topically Applied Betulinic Acid and NVX-207 on Melanocytic Tumors in 18 Horses.

Journal: Animals : an open access journal from MDPI

Published: October 04, 2021

Betulin Sulfonamides as Carbonic Anhydrase Inhibitors and Anticancer Agents in Breast Cancer Cells.

Betulin Sulfonamides as Carbonic Anhydrase Inhibitors and Anticancer Agents in Breast Cancer Cells.

Journal: International journal of molecular sciences

Published: June 16, 2021

MSBA-S - A pentacyclic sulfamate as a new option for radiotherapy of human breast cancer cells.

MSBA-S - A pentacyclic sulfamate as a new option for radiotherapy of human breast cancer cells.

Journal: European journal of medicinal chemistry

Published: April 25, 2021

Combined 3-O-acetylbetulin treatment and carbonic anhydrase IX inhibition results in additive effects on human breast cancer cells.

Combined 3-O-acetylbetulin treatment and carbonic anhydrase IX inhibition results in additive effects on human breast cancer cells.

Journal: Chemico-biological interactions

Published: July 24, 2020

Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.

Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.

Journal: Scientific data

Published: June 12, 2020

In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate as a topical treatment for equine skin cancer.

In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate as a topical treatment for equine skin cancer.

Journal: PloS one

Published: May 01, 2020

Evaluation of the Betulinic Acid-Cisplatin conjugate APC and its precursor DE9B for the treatment of human malignant glioma.

Evaluation of the Betulinic Acid-Cisplatin conjugate APC and its precursor DE9B for the treatment of human malignant glioma.

Journal: Chemico-biological interactions

Published: June 04, 2019

Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro.

Betulinic acid shows anticancer activity against equine melanoma cells and permeates isolated equine skin in vitro.

Journal: BMC veterinary research

Published: May 02, 2019

Synthesis and biological investigation of new carbonic anhydrase IX (CAIX) inhibitors.

Synthesis and biological investigation of new carbonic anhydrase IX (CAIX) inhibitors.

Journal: Chemico-biological interactions

Published: October 11, 2017

Showing 1-12 of 25

Last Updated: 09/26/2026