Reinis R. Ruza

South Parks Road
Oxford, ENG OX13QU, United Kingdom

Last Updated: 09/26/2026

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Found 15 publications

A pivot-tether model for nucleosome recognition by the chromosomal passenger complex.

A pivot-tether model for nucleosome recognition by the chromosomal passenger complex.

Journal: EMBO reports

Published: February 10, 2025

Structural insights into Frizzled3 through nanobody modulators.

Structural insights into Frizzled3 through nanobody modulators.

Journal: Nature communications

Published: November 21, 2023

Structural Analysis and Development of Notum Fragment Screening Hits.

Structural Analysis and Development of Notum Fragment Screening Hits.

Journal: ACS chemical neuroscience

Published: June 22, 2022

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.

Journal: Journal of medicinal chemistry

Published: May 10, 2022

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

Journal: Nature structural & molecular biology

Published: February 04, 2021

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit.

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit.

Journal: Journal of medicinal chemistry

Published: October 30, 2020

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

Journal: Nature structural & molecular biology

Published: October 16, 2020

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.

Journal: Cell host & microbe

Published: September 10, 2020

Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity.

Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity.

Journal: Journal of medicinal chemistry

Published: August 14, 2020

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.

Journal: Nature structural & molecular biology

Published: June 07, 2020

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

Journal: Nature structural & molecular biology

Published: May 21, 2020

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.

Journal: Cell host & microbe

Published: May 13, 2020

Showing 1-12 of 15

Last Updated: 09/26/2026