Rene Maltais

Quebec, QC G1V4G2, Canada

Last Updated: 09/26/2026

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Found 58 publications

Aminosteroid RM-581 Induces G0/G1 Arrest and Endoplasmic Reticulum Stress-Mediated Apoptosis in Human Acute and Chronic Leukemia Cell Lines.

Aminosteroid RM-581 Induces G0/G1 Arrest and Endoplasmic Reticulum Stress-Mediated Apoptosis in Human Acute and Chronic Leukemia Cell Lines.

Journal: Cancers

Published: February 21, 2026

Evaluation of combining the PDX analogue AN-137B with oseltamivir in a mouse model of severe influenza A (H1N1) infection.

Evaluation of combining the PDX analogue AN-137B with oseltamivir in a mouse model of severe influenza A (H1N1) infection.

Journal: Antiviral therapy

Published: December 09, 2025

Metabolite profiling in human and mouse liver microsomes of the aminosteroid RM-581, a new orally active anticancer agent.

Metabolite profiling in human and mouse liver microsomes of the aminosteroid RM-581, a new orally active anticancer agent.

Journal: Bioorganic chemistry

Published: June 18, 2025

Development of a Multigram Synthetic Route to RM-581, an Orally Active Aminosteroid Derivative Against Several Types of Cancers.

Development of a Multigram Synthetic Route to RM-581, an Orally Active Aminosteroid Derivative Against Several Types of Cancers.

Journal: Molecules (Basel, Switzerland)

Published: May 09, 2025

Synthesis and characterization of targeted 17β-hydroxysteroid dehydrogenase type 7 inhibitors.

Synthesis and characterization of targeted 17β-hydroxysteroid dehydrogenase type 7 inhibitors.

Journal: The Journal of steroid biochemistry and molecular biology

Published: April 05, 2024

Development of New Resolvin D1 Analogues for Osteoarthritis Therapy: Acellular and Computational Approaches to Study Their Antioxidant Activities.

Development of New Resolvin D1 Analogues for Osteoarthritis Therapy: Acellular and Computational Approaches to Study Their Antioxidant Activities.

Journal: Antioxidants (Basel, Switzerland)

Published: February 20, 2024

A protectin DX (PDX) analog with in vitro activity against influenza A(H1N1) viruses.

A protectin DX (PDX) analog with in vitro activity against influenza A(H1N1) viruses.

Journal: Journal of medical virology

Published: November 09, 2023

Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments.

Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments.

Journal: Journal of clinical medicine

Published: May 15, 2023

An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models.

An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models.

Journal: Cancers

Published: April 01, 2023

Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone.

Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone.

Journal: Molecules (Basel, Switzerland)

Published: December 01, 2022

Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution.

Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution.

Journal: Bioorganic chemistry

Published: June 20, 2022

An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis.

An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis.

Journal: The Journal of steroid biochemistry and molecular biology

Published: March 09, 2022

Showing 1-12 of 58

Last Updated: 09/26/2026