Richard B. Lock
Sydney, NSW, Australia
Last Updated: 09/26/2026
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Found 145 publications
Preclinical evaluation of the ROR1-targeting antibody-drug conjugates zilovertamab vedotin and VLS-211 against B-cell ALL patient-derived xenografts.
Journal: HemaSphere
Published: January 12, 2026
A novel CRLF2-targeted antibody-drug conjugate exhibits potent anti-leukemic activity against Ph-like acute lymphoblastic leukemia.
Journal: Leukemia
Published: November 10, 2025
BCL-2 and MCL1 co-inhibition enhances glucocorticoid therapy in preclinical models of infant KMT2A-rearranged acute lymphoblastic leukaemia.
Journal: British journal of haematology
Published: October 26, 2025
The myeloid cell leukaemia-1 inhibitor MIK665 is a potent therapy in preclinical models of paediatric acute myeloid leukaemia.
Journal: British journal of haematology
Published: August 14, 2025
Comprehensive Multiplatform Tyrosine Kinase Profiling Reveals Novel Actionable FGFR Aberrations across Sarcomas Affecting the Young.
Journal: Molecular cancer therapeutics
Published: July 01, 2025
Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across sarcomas affecting the young.
Journal: Molecular cancer therapeutics
Published: July 01, 2025
Patient-Specific Circulating Tumor DNA for Monitoring Response to Menin Inhibitor Treatment in Preclinical Models of Infant Leukemia.
Journal: Cancers
Published: October 11, 2024
The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia.
Journal: HemaSphere
Published: October 02, 2024
Immune-deficient MISTRG mice support expansion of leukaemia-initiating cells in xenograft models of paediatric acute myeloid leukaemia.
Journal: British journal of haematology
Published: September 26, 2024
The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia.
Journal: Blood cancer journal
Published: September 08, 2024
Lessons learned from 20 years of preclinical testing in pediatric cancers.
Journal: Pharmacology & therapeutics
Published: August 31, 2024
Last Updated: 09/26/2026