Richard G. Leduc

Sherbrooke, QC J1H5N4, Canada

Last Updated: 09/26/2026

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Found 83 publications

TMPRSS2 inhibitors with broad-spectrum efficacy against SARS-CoV-2 (JN.1) and influenza A (H1N1) viruses protect mice from influenza A infection.

TMPRSS2 inhibitors with broad-spectrum efficacy against SARS-CoV-2 (JN.1) and influenza A (H1N1) viruses protect mice from influenza A infection.

Journal: Emerging microbes & infections

Published: January 30, 2026

Tunable Biased Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Engineering and Allosteric Site Targeting.

Tunable Biased Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Engineering and Allosteric Site Targeting.

Journal: Journal of medicinal chemistry

Published: January 16, 2026

Profiling circular RNAs in amniotic fluid and fetal lungs from congenital diaphragmatic hernia cases: insights into potential prognostic and diagnostic applications.

Profiling circular RNAs in amniotic fluid and fetal lungs from congenital diaphragmatic hernia cases: insights into potential prognostic and diagnostic applications.

Journal: Pediatric surgery international

Published: January 09, 2026

Structure-Guided Optimization of Selective Covalent Reversible Peptidomimetic Inhibitors Targeting TMPRSS6.

Structure-Guided Optimization of Selective Covalent Reversible Peptidomimetic Inhibitors Targeting TMPRSS6.

Journal: Journal of medicinal chemistry

Published: December 05, 2025

Adhesion G protein-coupled receptors.

Adhesion G protein-coupled receptors.

Journal: Pharmacological reviews

Published: September 12, 2025

Structural insights into frog skin-derived cyclic peptides as selective matriptase inhibitors.

Structural insights into frog skin-derived cyclic peptides as selective matriptase inhibitors.

Journal: European journal of medicinal chemistry

Published: August 30, 2025

Decoding ADGRE5: How Proteolytic Cleavage and Mechanical Forces Unleash Cellular Signals.

Decoding ADGRE5: How Proteolytic Cleavage and Mechanical Forces Unleash Cellular Signals.

Journal: Cells

Published: July 18, 2025

Adhesion GPCR ADGRL1/Latrophilin-1 mobilizes β-arrestins as a prerequisite for endosomal restriction of G protein activation and splice-dependent scaffolds.

Adhesion GPCR ADGRL1/Latrophilin-1 mobilizes β-arrestins as a prerequisite for endosomal restriction of G protein activation and splice-dependent scaffolds.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: April 17, 2025

Adhesion GPCR ADGRL1/Latrophilin-1 mobilizes β-arrestins as a prerequisite for endosomal restriction of G protein activation and splice-dependent scaffolds.

Adhesion GPCR ADGRL1/Latrophilin-1 mobilizes β-arrestins as a prerequisite for endosomal restriction of G protein activation and splice-dependent scaffolds.

Journal: Biochimica et biophysica acta. Molecular cell research

Published: April 17, 2025

From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants.

From N-0385 to N-0920: Unveiling a Host-Directed Protease Inhibitor with Picomolar Antiviral Efficacy against Prevalent SARS-CoV-2 Variants.

Journal: Journal of medicinal chemistry

Published: March 31, 2025

Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency.

Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: February 20, 2025

Optimizing the pharmacokinetics and selectivity of TMPRSS2 inhibitors.

Optimizing the pharmacokinetics and selectivity of TMPRSS2 inhibitors.

Journal: European journal of medicinal chemistry

Published: February 18, 2025

Showing 1-12 of 83

Last Updated: 09/26/2026