Rob C. Hoeben

Leiden, ZH 2333ZA, Netherlands

Last Updated: 09/26/2026

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Found 99 publications

Improved oncolytic and immunostimulatory activity of the spontaneous jin-3 reovirus mutant in preclinical bladder cancer models.

Improved oncolytic and immunostimulatory activity of the spontaneous jin-3 reovirus mutant in preclinical bladder cancer models.

Journal: Molecular therapy. Oncology
Published: August 18, 2025

Selector adeno-associated viral vectors facilitate on-target precise genome editing and purge off-target chromosomal insertions.

Selector adeno-associated viral vectors facilitate on-target precise genome editing and purge off-target chromosomal insertions.

Journal: Trends in biotechnology
Published: June 23, 2025

Boosting CAR T cell functionality with oncolytic viruses for the treatment of pediatric diffuse midline gliomas.

Boosting CAR T cell functionality with oncolytic viruses for the treatment of pediatric diffuse midline gliomas.

Journal: Molecular therapy. Oncology
Published: June 23, 2025

Increasing the odds: antibody-mediated delivery of two distinct immunogenic T-cell epitopes with one antibody.

Increasing the odds: antibody-mediated delivery of two distinct immunogenic T-cell epitopes with one antibody.

Journal: Oncoimmunology
Published: May 27, 2025

A new adenovirus isolated from a western lowland gorilla held in captivity.

A new adenovirus isolated from a western lowland gorilla held in captivity.

Journal: Virology
Published: May 21, 2025

Unusual Partners: γδ-TCR-Based T Cell Therapy in Combination with Oncolytic Virus Treatment for Diffuse Midline Gliomas.

Unusual Partners: γδ-TCR-Based T Cell Therapy in Combination with Oncolytic Virus Treatment for Diffuse Midline Gliomas.

Journal: International journal of molecular sciences
Published: December 18, 2024

Immune Shielding of Human Heart Valves: A Proof-of-Concept Study of HLA-Targeting Therapy for Transplantations.

Immune Shielding of Human Heart Valves: A Proof-of-Concept Study of HLA-Targeting Therapy for Transplantations.

Journal: JACC. Basic to translational science
Published: May 01, 2024

Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces.

Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces.

Journal: mAbs
Published: March 18, 2024

Precision genome editing using combinatorial viral vector delivery of CRISPR-Cas9 nucleases and donor DNA constructs.

Precision genome editing using combinatorial viral vector delivery of CRISPR-Cas9 nucleases and donor DNA constructs.

Journal: Nucleic acids research
Published: March 15, 2024

The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles.

The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles.

Journal: Molecular therapy. Oncology
Published: October 11, 2023

Antibody-mediated delivery of viral epitopes to redirect EBV-specific CD8+ T-cell immunity towards cancer cells.

Antibody-mediated delivery of viral epitopes to redirect EBV-specific CD8+ T-cell immunity towards cancer cells.

Journal: Cancer gene therapy
Published: July 25, 2023

Neutralizing Antibodies Impair the Oncolytic Efficacy of Reovirus but Permit Effective Combination with T cell-Based Immunotherapies.

Neutralizing Antibodies Impair the Oncolytic Efficacy of Reovirus but Permit Effective Combination with T cell-Based Immunotherapies.

Journal: Cancer immunology research
Published: June 08, 2023
Showing 1-12 of 99

Last Updated: 09/26/2026