Rob N. De Jong
Utrecht, UT 3584CT, Netherlands
Last Updated: 09/26/2026
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Found 18 publications
A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade.
Journal: Scientific reports
Published: March 20, 2025
Biophysical Characterization and Stability of Modified IgG1 Antibodies with Different Hexamerization Propensities.
Journal: Journal of pharmaceutical sciences
Published: September 03, 2021
Logic-gated antibody pairs that selectively act on cells co-expressing two antigens.
Journal: Nature biotechnology
Published: March 30, 2021
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 10, 2021
CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.
Journal: Haematologica
Published: October 02, 2018
Kinetic mechanism of controlled Fab-arm exchange for the formation of bispecific immunoglobulin G1 antibodies.
Journal: The Journal of biological chemistry
Published: October 05, 2017
Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement.
Journal: Science (New York, N.Y.)
Published: July 27, 2017
Real-time analysis of the detailed sequence of cellular events in mAb-mediated complement-dependent cytotoxicity of B-cell lines and of chronic lymphocytic leukemia B-cells.
Journal: Molecular immunology
Published: November 06, 2015
A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface.
Journal: PLoS biology
Published: August 20, 2015
Last Updated: 09/26/2026