Robbert H. Cool

Groningen, GR 9713AV, Netherlands

Last Updated: 09/26/2026

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Found 28 publications

Discovery of Furan-2-Carboxylic Acid Derivatives as Novel D-Dopachrome Tautomerase (D-DT) and Macrophage Migration Inhibitory Factor-1 (MIF-1) Dual Inhibitors.

Discovery of Furan-2-Carboxylic Acid Derivatives as Novel D-Dopachrome Tautomerase (D-DT) and Macrophage Migration Inhibitory Factor-1 (MIF-1) Dual Inhibitors.

Journal: Journal of medicinal chemistry

Published: March 02, 2026

Receptor agonist of NFκB signaling ligand directs lung epithelial cell expansion through RANK signaling.

Receptor agonist of NFκB signaling ligand directs lung epithelial cell expansion through RANK signaling.

Journal: American journal of physiology. Lung cellular and molecular physiology

Published: January 28, 2026

Receptor agonist of NFκB signaling ligand directs lung epithelial cell expansion through RANK signaling.

Receptor agonist of NFκB signaling ligand directs lung epithelial cell expansion through RANK signaling.

Journal: American journal of physiology. Lung cellular and molecular physiology

Published: January 28, 2026

Correction to "Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells".

Correction to "Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells".

Journal: Journal of medicinal chemistry

Published: March 10, 2025

Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos.

Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos.

Journal: Journal of medicinal chemistry

Published: June 23, 2023

Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells.

Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells.

Journal: Journal of medicinal chemistry

Published: January 18, 2022

4-Iodopyrimidine Labeling Reveals Nuclear Translocation and Nuclease Activity for Both MIF and MIF2.

4-Iodopyrimidine Labeling Reveals Nuclear Translocation and Nuclease Activity for Both MIF and MIF2.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: August 18, 2021

Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells.

Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells.

Journal: Angewandte Chemie (International ed. in English)

Published: February 05, 2021

7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor.

7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor.

Journal: Journal of medicinal chemistry

Published: September 17, 2020

D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling.

D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling.

Journal: EBioMedicine

Published: July 06, 2020

Cross-kingdom mimicry of the receptor signaling and leukocyte recruitment activity of a human cytokine by its plant orthologs.

Cross-kingdom mimicry of the receptor signaling and leukocyte recruitment activity of a human cytokine by its plant orthologs.

Journal: The Journal of biological chemistry

Published: June 07, 2019

Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models.

Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models.

Journal: Cancers

Published: May 03, 2019

Showing 1-12 of 28

Last Updated: 09/26/2026