Last Updated: 09/26/2026
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Found 29 publications
How to Replace the TQT Study-The Use of Concentration-QTc Modeling to Exclude a Small Effect of a Novel Drug on QT Interval: Historical Perspective and Implementation.
Journal: Journal of clinical pharmacology
Published: April 29, 2026
Cardiodynamic evaluation of sorfequiline (TBAJ-876): results from a first-in-human study.
Journal: Antimicrobial agents and chemotherapy
Published: January 30, 2026
Corrigendum to "Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As" [J. Pharmacol. Toxicol. Methods 123 (2023) 107270].
Journal: Journal of pharmacological and toxicological methods
Published: September 16, 2025
Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT Study.
Journal: Drug design, development and therapy
Published: September 03, 2025
Low Proarrhythmic Risk of Imetelstat, a Novel Oligonucleotide Telomerase Inhibitor: A Translational Analysis.
Journal: Clinical and translational science
Published: October 02, 2024
An overview of drug-induced sodium channel blockade and changes in cardiac conduction: Implications for drug safety.
Journal: Clinical and translational science
Published: July 25, 2024
Validation of a Handheld 6-Lead Device for QT Interval Monitoring in Resource-Limited Settings.
Journal: JAMA network open
Published: June 07, 2024
Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.
Journal: Journal of pharmacological and toxicological methods
Published: March 08, 2024
Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As.
Journal: Journal of pharmacological and toxicological methods
Published: February 20, 2023
Improving the in Vivo QTc assay: The value of implementing best practices to support an integrated nonclinical-clinical QTc risk assessment and TQT substitute.
Journal: Journal of pharmacological and toxicological methods
Published: February 17, 2023
Ventricular Arrhythmias Associated With Over-the-Counter and Recreational Opioids.
Journal: Journal of the American College of Cardiology
Published: January 30, 2023
False Negative ECG Device Results May Increase the Risk of Adverse Events in Clinical Oncology Trials.
Journal: Therapeutic innovation & regulatory science
Published: February 02, 2022
Last Updated: 09/26/2026