Robert G. Roth

AstraZeneca R&D
Moelndal, O, Sweden

Last Updated: 09/26/2026

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Found 15 publications

Discovery of a Highly Potent and Selective Small-Molecule Inhibitor of In Vivo Anaerobic Choline Metabolism by Human Gut Bacteria.

Discovery of a Highly Potent and Selective Small-Molecule Inhibitor of In Vivo Anaerobic Choline Metabolism by Human Gut Bacteria.

Journal: Journal of medicinal chemistry

Published: January 30, 2026

Protein Expression via Transient Transfection of Mammalian Cells in a WAVE Bioreactor.

Protein Expression via Transient Transfection of Mammalian Cells in a WAVE Bioreactor.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: June 26, 2024

FRAGLER: A Fragment Recycler Application Enabling Rapid and Scalable Modular DNA Assembly.

FRAGLER: A Fragment Recycler Application Enabling Rapid and Scalable Modular DNA Assembly.

Journal: ACS synthetic biology

Published: July 07, 2022

The Common H202D Variant in GDF-15 Does Not Affect Its Bioactivity but Can Significantly Interfere with Measurement of Its Circulating Levels.

The Common H202D Variant in GDF-15 Does Not Affect Its Bioactivity but Can Significantly Interfere with Measurement of Its Circulating Levels.

Journal: The journal of applied laboratory medicine

Published: January 11, 2022

Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.

Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.

Journal: Metabolic engineering

Published: November 23, 2021

Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.

Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.

Journal: Clinical & translational immunology

Published: February 10, 2021

Refolding and purification of cGMP-grade recombinant human neurturin from Escherichia coli inclusion bodies.

Refolding and purification of cGMP-grade recombinant human neurturin from Escherichia coli inclusion bodies.

Journal: Protein expression and purification

Published: November 06, 2019

Systematic Evaluation of CRISPRa and CRISPRi Modalities Enables Development of a Multiplexed, Orthogonal Gene Activation and Repression System.

Systematic Evaluation of CRISPRa and CRISPRi Modalities Enables Development of a Multiplexed, Orthogonal Gene Activation and Repression System.

Journal: ACS synthetic biology

Published: August 10, 2019

Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain.

Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain.

Journal: Science advances

Published: June 11, 2018

Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.

Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.

Journal: ACS medicinal chemistry letters

Published: December 05, 2017

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.

Journal: ACS medicinal chemistry letters

Published: December 04, 2017

Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.

Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.

Journal: The Journal of biological chemistry

Published: November 09, 2017

Showing 1-12 of 15

Last Updated: 09/26/2026