Robert I. Lechler

London, ENG SE19RT, United Kingdom

Last Updated: 09/26/2026

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Found 81 publications

Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease.

Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease.

Journal: EBioMedicine

Published: March 07, 2023

Radiolabelling of Polyclonally Expanded Human Regulatory T Cells (Treg) with 89Zr-oxine for Medium-Term In Vivo Cell Tracking.

Radiolabelling of Polyclonally Expanded Human Regulatory T Cells (Treg) with 89Zr-oxine for Medium-Term In Vivo Cell Tracking.

Journal: Molecules (Basel, Switzerland)

Published: December 15, 2022

Inhibition of thrombin on endothelium enhances recruitment of regulatory T cells during IRI and when combined with adoptive Treg transfer, significantly protects against acute tissue injury and prolongs allograft survival.

Inhibition of thrombin on endothelium enhances recruitment of regulatory T cells during IRI and when combined with adoptive Treg transfer, significantly protects against acute tissue injury and prolongs allograft survival.

Journal: Frontiers in immunology

Published: June 28, 2022

Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency.

Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency.

Journal: JCI insight

Published: March 04, 2021

The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease.

The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Published: March 02, 2021

Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance?

Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance?

Journal: European journal of immunology

Published: November 30, 2020

Translational Research in the Time of COVID-19-Dissolving Boundaries.

Translational Research in the Time of COVID-19-Dissolving Boundaries.

Journal: PLoS pathogens

Published: September 30, 2020

Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients.

Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Published: September 08, 2020

Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment.

Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment.

Journal: Molecular therapy. Methods & clinical development

Published: September 07, 2020

Isolation and expansion of thymus-derived regulatory T cells for use in pediatric heart transplant patients.

Isolation and expansion of thymus-derived regulatory T cells for use in pediatric heart transplant patients.

Journal: European journal of immunology

Published: September 01, 2020

Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive.

Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive.

Journal: European journal of immunology

Published: August 21, 2020

PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.

PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.

Journal: PLoS biology

Published: June 15, 2020

Showing 1-12 of 81

Last Updated: 09/26/2026