Robert Lukowski

Tuebingen, BW, Germany

Last Updated: 09/26/2026

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Found 84 publications

Use of soluble guanylyl cyclase stimulators in heart failure therapy-a mode of action perspective.

Use of soluble guanylyl cyclase stimulators in heart failure therapy-a mode of action perspective.

Journal: ESC heart failure
Published: October 10, 2025

CYR119, a central nervous system-penetrant stimulator of soluble guanylyl cyclase, improves survival in a mouse model of resuscitation after cardiac arrest.

CYR119, a central nervous system-penetrant stimulator of soluble guanylyl cyclase, improves survival in a mouse model of resuscitation after cardiac arrest.

Journal: Nitric oxide : biology and chemistry
Published: July 28, 2025

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3-L1 adipocytes.

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3-L1 adipocytes.

Journal: British journal of pharmacology
Published: June 13, 2025

Nociceptor-specific signaling of the receptor guanylyl cyclase Npr2 contributes to acute and persistent pain.

Nociceptor-specific signaling of the receptor guanylyl cyclase Npr2 contributes to acute and persistent pain.

Journal: Science signaling
Published: June 03, 2025

Slick K+ channels contribute to cardiac remodeling, fibrosis, and dysfunction in postinfarction hearts.

Slick K+ channels contribute to cardiac remodeling, fibrosis, and dysfunction in postinfarction hearts.

Journal: JCI insight
Published: May 21, 2025

p21-activated kinases (PAKs) regulate FGF1/PDE4D antilipolytic pathway and insulin resistance in adipocytes.

p21-activated kinases (PAKs) regulate FGF1/PDE4D antilipolytic pathway and insulin resistance in adipocytes.

Journal: Molecular metabolism
Published: April 21, 2025

Targeting hexokinase 2 to induce breast cancer cell senescence.

Targeting hexokinase 2 to induce breast cancer cell senescence.

Journal: British journal of pharmacology
Published: February 21, 2025

Tamoxifen metabolites acting via BKCa orchestrate the dynamics of K+ and Ca2+ in breast cancer cells.

Tamoxifen metabolites acting via BKCa orchestrate the dynamics of K+ and Ca2+ in breast cancer cells.

Journal: The Journal of biological chemistry
Published: January 26, 2025

Targeting Cyclophilin A in the Cardiac Microenvironment Preserves Heart Function and Structure in Failing Hearts.

Targeting Cyclophilin A in the Cardiac Microenvironment Preserves Heart Function and Structure in Failing Hearts.

Journal: Circulation research
Published: August 14, 2024

Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin+ myofibroblasts.

Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin+ myofibroblasts.

Journal: Clinical science (London, England : 1979)
Published: June 26, 2024

mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming.

mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming.

Journal: eLife
Published: May 29, 2024

Physioxia rewires mitochondrial complex composition to protect stem cell viability.

Physioxia rewires mitochondrial complex composition to protect stem cell viability.

Journal: Redox biology
Published: May 27, 2024
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Last Updated: 09/26/2026