Robert M. Chamuleau
Amsterdam, NH 1105BK, Netherlands
Last Updated: 09/26/2026
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Found 29 publications
Overexpression of the constitutive androstane receptor and shaken 3D-culturing increase biotransformation and oxidative phosphorylation and sensitivity to mitochondrial amiodarone toxicity of HepaRG cells.
Journal: Toxicology and applied pharmacology
Published: January 27, 2020
Genome-wide expression profiling reveals increased stability and mitochondrial energy metabolism of the human liver cell line HepaRG-CAR.
Journal: Cytotechnology
Published: November 25, 2019
End-stage liver failure: filling the treatment gap at the intensive care unit.
Journal: Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs
Published: July 11, 2019
Overexpression of carbamoyl-phosphate synthase 1 significantly improves ureagenesis of human liver HepaRG cells only when cultured under shaking conditions.
Journal: Mitochondrion
Published: October 16, 2018
Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines.
Journal: Journal of cell communication and signaling
Published: November 30, 2017
A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines.
Journal: PloS one
Published: October 25, 2017
HepaRG-Progenitor Cell Derived Hepatocytes Cultured in Bioartificial Livers Are Protected from Healthy- and Acute Liver Failure-Plasma Induced Toxicity.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Published: August 29, 2017
AMC-Bio-Artificial Liver culturing enhances mitochondrial biogenesis in human liver cell lines: The role of oxygen, medium perfusion and 3D configuration.
Journal: Mitochondrion
Published: May 12, 2017
Stable Overexpression of the Constitutive Androstane Receptor Reduces the Requirement for Culture with Dimethyl Sulfoxide for High Drug Metabolism in HepaRG Cells.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: July 20, 2016
Selecting Cells for Bioartificial Liver Devices and the Importance of a 3D Culture Environment: A Functional Comparison between the HepaRG and C3A Cell Lines.
Journal: International journal of biological sciences
Published: February 01, 2016
Pivotal preclinical trial of the spheroid reservoir bioartificial liver.
Journal: Journal of hepatology
Published: May 16, 2015
Last Updated: 09/26/2026