Last Updated: 09/26/2026
Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 22 publications
Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.
Journal: ACS medicinal chemistry letters
Published: April 02, 2021
Correction to Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.
Journal: ACS medicinal chemistry letters
Published: June 20, 2020
Understanding Pharmacokinetic Disconnect in Preclinical Species for 4-Aminoquinolines: Consequences of Low Permeability and High P-glycoprotein Efflux Ratio on Rat and Dog Oral Pharmacokinetics.
Journal: Journal of pharmaceutical sciences
Published: April 28, 2020
Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases.
Journal: Journal of medicinal chemistry
Published: July 03, 2019
Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity.
Journal: Nature
Published: May 31, 2019
Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.
Journal: ACS medicinal chemistry letters
Published: March 29, 2019
Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer.
Journal: ACS medicinal chemistry letters
Published: March 15, 2019
Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.
Journal: ACS medicinal chemistry letters
Published: July 27, 2018
Design of amidobenzimidazole STING receptor agonists with systemic activity.
Journal: Nature
Published: June 22, 2018
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
Journal: Journal of medicinal chemistry
Published: February 03, 2017
Usage of an Electronic Database and Checklist System for Improvement in Magnetic Resonance Imaging Acquisition.
Journal: Current problems in diagnostic radiology
Published: January 15, 2017
The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase.
Journal: Journal of medicinal chemistry
Published: April 26, 2016
Last Updated: 09/26/2026