Robert Wheller

Fordham, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 11 publications

Design of experiments for the optimization of sample preparation for bottom-up targeted protein LC-MS/MS workflows.

Design of experiments for the optimization of sample preparation for bottom-up targeted protein LC-MS/MS workflows.

Journal: Bioanalysis

Published: June 10, 2025

The use of surrogate matrices in bioanalytical preclinical safety testing using chromatographic methods: a recommendation from the European Bioanalysis forum.

The use of surrogate matrices in bioanalytical preclinical safety testing using chromatographic methods: a recommendation from the European Bioanalysis forum.

Journal: Bioanalysis

Published: October 23, 2024

Recommendations and feedback from the European Bioanalysis Forum Workshop: 1 year into ICH M10 - keeping our finger on the pulse.

Recommendations and feedback from the European Bioanalysis Forum Workshop: 1 year into ICH M10 - keeping our finger on the pulse.

Journal: Bioanalysis

Published: February 05, 2024

Single-day protein LC-MS bioanalysis: can next-generation trypsins cut it?

Single-day protein LC-MS bioanalysis: can next-generation trypsins cut it?

Journal: Bioanalysis

Published: April 11, 2023

Development and validation of a liquid chromatography-triple quadrupole mass spectrometry method for the determination of isopeptide ε-(γ-glutamyl) lysine in human urine as biomarker for transglutaminase 2 cross-linked proteins.

Development and validation of a liquid chromatography-triple quadrupole mass spectrometry method for the determination of isopeptide ε-(γ-glutamyl) lysine in human urine as biomarker for transglutaminase 2 cross-linked proteins.

Journal: Journal of chromatography. A

Published: February 03, 2023

Recommendations on qPCR/ddPCR assay validation by GCC.

Recommendations on qPCR/ddPCR assay validation by GCC.

Journal: Bioanalysis

Published: June 15, 2022

2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).

2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs (Part 1A - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).

Journal: Bioanalysis

Published: May 17, 2022

Recommendations on ELISpot assay validation by the GCC.

Recommendations on ELISpot assay validation by the GCC.

Journal: Bioanalysis

Published: February 09, 2022

Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study.

Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study.

Journal: BMJ open diabetes research & care

Published: November 23, 2019

Internal standards in regulated bioanalysis: putting in place a decision-making process during method development.

Internal standards in regulated bioanalysis: putting in place a decision-making process during method development.

Journal: Bioanalysis

Published: October 25, 2019

Glu-C, an alternative digestive enzyme for the quantitative LC-MS/MS analysis of an IgG-based antibody biotherapeutic.

Glu-C, an alternative digestive enzyme for the quantitative LC-MS/MS analysis of an IgG-based antibody biotherapeutic.

Journal: Bioanalysis

Published: July 05, 2018

Showing 1-11 of 11

Last Updated: 09/26/2026