Roberta Santarelli
Rome, 00161, Italy
Last Updated: 09/26/2026
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Found 57 publications
HHV-6A Drives Epigenetic Reprogramming via an EZH2-SIRT1 Axis to Sustain Mutant p53 and Reshape Oncogenic Inflammatory Signaling.
Journal: Viruses
Published: February 24, 2026
The yin and yang interplay between HDAC6 and KDM1 regulates the lysosomal degradation of mutp53 in colon cancer cells undergoing TG-induced ER stress.
Journal: Biochimica et biophysica acta. Molecular cell research
Published: January 28, 2026
Acetylation promotes mutant (MUT) TP53-HSPA8 and HSPA8-BAG3 interactions, facilitating MUT TP53 lysosomal degradation preferentially via CASA.
Journal: Autophagy
Published: October 16, 2025
Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cells.
Journal: Cell death discovery
Published: August 29, 2025
Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells.
Journal: Biomedicines
Published: July 23, 2025
Modulatory Effect of Curcumin on Expression of Methyltransferase/Demethylase in Colon Cancer Cells: Impact on wt p53, mutp53 and c-Myc.
Journal: Molecules (Basel, Switzerland)
Published: June 11, 2025
Changes in Lysine Methylation Contribute to the Cytotoxicity of Curcumin in Colon Cancer Cells.
Journal: Molecules (Basel, Switzerland)
Published: December 05, 2024
EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?
Journal: Biochimica et biophysica acta. Gene regulatory mechanisms
Published: June 10, 2024
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice.
Journal: Microbiology spectrum
Published: October 26, 2023
Last Updated: 09/26/2026