Roberto Villasenor

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 23 publications

Impact of ASO conjugation and receptor binding affinity on intracellular transport of mono- and bispecific TfR- and CD98-BrainshuttleTM variants.

Impact of ASO conjugation and receptor binding affinity on intracellular transport of mono- and bispecific TfR- and CD98-BrainshuttleTM variants.

Journal: mAbs

Published: June 22, 2026

An alternative nonclinical approach to support the first-in-human clinical trial of a T-cell bispecific targeting EGFRvIII.

An alternative nonclinical approach to support the first-in-human clinical trial of a T-cell bispecific targeting EGFRvIII.

Journal: Journal of pharmaceutical sciences

Published: July 09, 2025

A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular anti-sense oligonucleotide activity.

A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular anti-sense oligonucleotide activity.

Journal: Nature communications

Published: January 09, 2025

ApoE4 disrupts intracellular trafficking and iron homeostasis in a reproducible iPSC-based model of human brain endothelial cells.

ApoE4 disrupts intracellular trafficking and iron homeostasis in a reproducible iPSC-based model of human brain endothelial cells.

Journal: Stem cell reports

Published: October 26, 2024

Advanced tissue technologies of blood-brain barrier organoids as high throughput toxicity readouts in drug development.

Advanced tissue technologies of blood-brain barrier organoids as high throughput toxicity readouts in drug development.

Journal: Heliyon

Published: September 12, 2024

Author Correction: High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression.

Author Correction: High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression.

Journal: Nature communications

Published: November 30, 2022

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct.

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct.

Journal: Nature communications

Published: April 01, 2022

High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression.

High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression.

Journal: Nature communications

Published: December 22, 2021

High Throughput Blood-brain Barrier Organoid Generation and Assessment of Receptor-Mediated Antibody Transcytosis.

High Throughput Blood-brain Barrier Organoid Generation and Assessment of Receptor-Mediated Antibody Transcytosis.

Journal: Bio-protocol

Published: December 17, 2021

Microphysiological Neurovascular Barriers to Model the Inner Retinal Microvasculature.

Microphysiological Neurovascular Barriers to Model the Inner Retinal Microvasculature.

Journal: Journal of personalized medicine

Published: December 15, 2021

Investigating receptor-mediated antibody transcytosis using blood-brain barrier organoid arrays.

Investigating receptor-mediated antibody transcytosis using blood-brain barrier organoid arrays.

Journal: Fluids and barriers of the CNS

Published: March 25, 2021

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.

Journal: Nature neuroscience

Published: November 12, 2020

Showing 1-12 of 23

Last Updated: 09/26/2026