Roel C. Janssens

Rotterdam, ZH, Netherlands

Last Updated: 09/26/2026

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Found 19 publications

Dual Modes of Gene Regulation by CDK12.

Dual Modes of Gene Regulation by CDK12.

Journal: bioRxiv : the preprint server for biology

Published: October 03, 2025

Residual CSB activity explains mild UV-sensitive syndrome phenotype caused by CSB mutations.

Residual CSB activity explains mild UV-sensitive syndrome phenotype caused by CSB mutations.

Journal: The Journal of investigative dermatology

Published: September 30, 2025

STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.

STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.

Journal: Molecular cell

Published: June 04, 2024

Differential processing of RNA polymerase II at DNA damage correlates with transcription-coupled repair syndrome severity.

Differential processing of RNA polymerase II at DNA damage correlates with transcription-coupled repair syndrome severity.

Journal: Nucleic acids research

Published: December 22, 2023

Live-cell imaging of endogenous CSB-mScarletI as a sensitive marker for DNA-damage-induced transcription stress.

Live-cell imaging of endogenous CSB-mScarletI as a sensitive marker for DNA-damage-induced transcription stress.

Journal: Cell reports methods

Published: July 18, 2023

Transcription-coupled DNA-protein crosslink repair by CSB and CRL4CSA-mediated degradation.

Transcription-coupled DNA-protein crosslink repair by CSB and CRL4CSA-mediated degradation.

Journal: Nature cell biology

Published: April 15, 2023

ATXN3 controls DNA replication and transcription by regulating chromatin structure.

ATXN3 controls DNA replication and transcription by regulating chromatin structure.

Journal: Nucleic acids research

Published: July 12, 2022

Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

Journal: Nature cell biology

Published: June 24, 2021

DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II.

DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II.

Journal: Nature communications

Published: December 04, 2020

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

Journal: Nature cell biology

Published: June 24, 2020

DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering.

DNA damage and transcription stress cause ATP-mediated redesign of metabolism and potentiation of anti-oxidant buffering.

Journal: Nature communications

Published: October 21, 2018

Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II.

Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 11, 2018

Showing 1-12 of 19

Last Updated: 09/26/2026