Roel Polak

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 12 publications

Organoid modeling of tumor-associated macrophages reveals phagocytosis checkpoint blockade-induced conversion to an immunosuppressive SPP1+ phenotype.

Organoid modeling of tumor-associated macrophages reveals phagocytosis checkpoint blockade-induced conversion to an immunosuppressive SPP1+ phenotype.

Journal: bioRxiv : the preprint server for biology
Published: May 18, 2026

Late toxicity after upper abdominal radiotherapy in pediatric Wilms tumor and neuroblastoma survivors. A systematic review on behalf of SIOPEN and SIOP-RTSG.

Late toxicity after upper abdominal radiotherapy in pediatric Wilms tumor and neuroblastoma survivors. A systematic review on behalf of SIOPEN and SIOP-RTSG.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published: January 29, 2025

Locoregional control in high-risk neuroblastoma using highly-conformal image-guided radiotherapy, with reduced margins and a boost dose for residual lesions.

Locoregional control in high-risk neuroblastoma using highly-conformal image-guided radiotherapy, with reduced margins and a boost dose for residual lesions.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published: July 27, 2024

Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment.

Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment.

Journal: Nature reviews. Cancer
Published: May 09, 2024

Engineered CD47 protects T cells for enhanced antitumour immunity.

Engineered CD47 protects T cells for enhanced antitumour immunity.

Journal: Nature
Published: May 08, 2023

Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1-driven B-cell precursor acute lymphoblastic leukemia.

Autophagy inhibition as a potential future targeted therapy for ETV6-RUNX1-driven B-cell precursor acute lymphoblastic leukemia.

Journal: Haematologica
Published: March 18, 2018

Megakaryocyte lineage development is controlled by modulation of protein acetylation.

Megakaryocyte lineage development is controlled by modulation of protein acetylation.

Journal: PloS one
Published: December 31, 2017

Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions.

Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions.

Journal: Frontiers in molecular neuroscience
Published: August 06, 2017

Acute lymphoblastic leukemia cells create a leukemic niche without affecting the CXCR4/CXCL12 axis.

Acute lymphoblastic leukemia cells create a leukemic niche without affecting the CXCR4/CXCL12 axis.

Journal: Haematologica
Published: June 17, 2017

Tunneling nanotubes facilitate autophagosome transfer in the leukemic niche.

Tunneling nanotubes facilitate autophagosome transfer in the leukemic niche.

Journal: Leukemia
Published: April 13, 2017

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment.

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment.

Journal: Blood
Published: March 16, 2015

The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia.

The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia.

Journal: Blood
Published: November 09, 2011
Showing 1-12 of 12

Last Updated: 09/26/2026