Roeland Vanhoutte

Leuven, VLG 3000, Belgium

Last Updated: 09/26/2026

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Found 14 publications

4-Oxo-β-lactams as Covalent Inhibitors of the Mitochondrial Intramembrane Protease PARL.

4-Oxo-β-lactams as Covalent Inhibitors of the Mitochondrial Intramembrane Protease PARL.

Journal: ACS medicinal chemistry letters

Published: August 02, 2024

Phosphinate Esters as Novel Warheads for Quenched Activity-Based Probes Targeting Serine Proteases.

Phosphinate Esters as Novel Warheads for Quenched Activity-Based Probes Targeting Serine Proteases.

Journal: ACS chemical biology

Published: June 24, 2024

Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions.

Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions.

Journal: JCI insight

Published: January 11, 2024

Metabolic support by macrophages sustains colonic epithelial homeostasis.

Metabolic support by macrophages sustains colonic epithelial homeostasis.

Journal: Cell metabolism

Published: December 26, 2022

Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System.

Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System.

Journal: Biomolecules

Published: December 15, 2022

Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells.

Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells.

Journal: Chemical science

Published: July 25, 2022

Combinatorial Optimization of Activity-Based Probes for Acyl Protein Thioesterases 1 and 2.

Combinatorial Optimization of Activity-Based Probes for Acyl Protein Thioesterases 1 and 2.

Journal: ACS medicinal chemistry letters

Published: July 21, 2022

Rapid Solid-Phase Construction of Serine Hydrolase Probes Results in Selective Activity-Based Probes for Acyl Protein Thioesterases-1/2.

Rapid Solid-Phase Construction of Serine Hydrolase Probes Results in Selective Activity-Based Probes for Acyl Protein Thioesterases-1/2.

Journal: Journal of medicinal chemistry

Published: September 29, 2020

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system.

ATP13A3 is a major component of the enigmatic mammalian polyamine transport system.

Journal: The Journal of biological chemistry

Published: April 15, 2020

Activity-Based Protein Profiling of Serine Proteases in Immune Cells.

Activity-Based Protein Profiling of Serine Proteases in Immune Cells.

Journal: Archivum immunologiae et therapiae experimentalis

Published: October 31, 2019

ATP13A2 deficiency disrupts lysosomal polyamine export.

ATP13A2 deficiency disrupts lysosomal polyamine export.

Journal: Nature

Published: December 21, 2018

Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X.

Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X.

Journal: ChemMedChem

Published: November 21, 2018

Showing 1-12 of 14

Last Updated: 09/26/2026