Roelof J. Smit

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 51 publications

Rare coding variant architecture and gene discovery from 130,000 sequenced cases of atrial fibrillation.

Rare coding variant architecture and gene discovery from 130,000 sequenced cases of atrial fibrillation.

Journal: Research square

Published: May 18, 2026

Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.

Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.

Journal: Research square

Published: April 10, 2026

Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.

Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations.

Journal: Research square

Published: April 10, 2026

Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms.

Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms.

Journal: Gut

Published: March 16, 2026

Association of genetic risk and physical activity with incident type 2 diabetes.

Association of genetic risk and physical activity with incident type 2 diabetes.

Journal: The Journal of clinical endocrinology and metabolism

Published: October 09, 2025

Polygenic risk score for type 2 diabetes shows context-dependent effects across populations.

Polygenic risk score for type 2 diabetes shows context-dependent effects across populations.

Journal: Nature communications

Published: April 08, 2025

Genome-wide association study provides novel insight into the genetic architecture of severe obesity.

Genome-wide association study provides novel insight into the genetic architecture of severe obesity.

Journal: PLoS genetics

Published: March 13, 2025

Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities.

Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities.

Journal: medRxiv : the preprint server for health sciences

Published: March 10, 2025

Type 2 diabetes polygenic risk score demonstrates context-dependent effects and associations with type 2 diabetes-related risk factors and complications across diverse populations.

Type 2 diabetes polygenic risk score demonstrates context-dependent effects and associations with type 2 diabetes-related risk factors and complications across diverse populations.

Journal: medRxiv : the preprint server for health sciences

Published: March 04, 2025

Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities.

Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities.

Journal: Nature medicine

Published: February 26, 2025

Polygenic prediction of body mass index and obesity through the life course and across ancestries.

Polygenic prediction of body mass index and obesity through the life course and across ancestries.

Journal: Nature medicine

Published: October 31, 2024

Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery: a multi-ancestry study in 10 960 individuals from 9 biobanks.

Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery: a multi-ancestry study in 10 960 individuals from 9 biobanks.

Journal: medRxiv : the preprint server for health sciences

Published: September 24, 2024

Showing 1-12 of 51

Last Updated: 09/26/2026