Roger Sandhoff

Heidelberg, BW, Germany

Last Updated: 09/26/2026

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Found 61 publications

Predicting GD2 expression across cancer types by the integration of pathway topology and transcriptome data.

Predicting GD2 expression across cancer types by the integration of pathway topology and transcriptome data.

Journal: Frontiers in bioinformatics
Published: September 15, 2025

The SGLT2 Inhibitor Dapagliflozin Disrupts the Cell Cycle at High Concentrations Without Altering Glycosphingolipid (De Novo)Biosynthesis.

The SGLT2 Inhibitor Dapagliflozin Disrupts the Cell Cycle at High Concentrations Without Altering Glycosphingolipid (De Novo)Biosynthesis.

Journal: International journal of molecular sciences
Published: August 20, 2025

Ganglioside Profiling Uncovers Distinct Patterns in High-Risk Neuroblastoma.

Ganglioside Profiling Uncovers Distinct Patterns in High-Risk Neuroblastoma.

Journal: International journal of molecular sciences
Published: August 01, 2025

Wnt-associated DKK3 in keratinocytes mediates radiation-induced hyperplasia, dermatitis and skin fibrosis.

Wnt-associated DKK3 in keratinocytes mediates radiation-induced hyperplasia, dermatitis and skin fibrosis.

Journal: Signal transduction and targeted therapy
Published: January 16, 2025

Glucosylceramide Synthase Inhibition in Combination with Aripiprazole Sensitizes Hepatocellular Cancer Cells to Sorafenib and Doxorubicin.

Glucosylceramide Synthase Inhibition in Combination with Aripiprazole Sensitizes Hepatocellular Cancer Cells to Sorafenib and Doxorubicin.

Journal: International journal of molecular sciences
Published: November 21, 2024

Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos.

Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos.

Journal: Science immunology
Published: April 19, 2024

Autosomal Dominant Lamellar Ichthyosis Due to a Missense Variant in the Gene NKPD1.

Autosomal Dominant Lamellar Ichthyosis Due to a Missense Variant in the Gene NKPD1.

Journal: The Journal of investigative dermatology
Published: January 15, 2024

Unraveling the glycosphingolipid metabolism by leveraging transcriptome-weighted network analysis on neuroblastic tumors.

Unraveling the glycosphingolipid metabolism by leveraging transcriptome-weighted network analysis on neuroblastic tumors.

Journal: Cancer & metabolism
Published: January 15, 2024

Lipid Structure Matters in Lysosomal Storage Disease.

Lipid Structure Matters in Lysosomal Storage Disease.

Journal: Journal of lipid research
Published: October 17, 2023

Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma.

Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma.

Journal: Nature communications
Published: June 24, 2023

Glucosylceramide Synthase Inhibitors Induce Ceramide Accumulation and Sensitize H3K27 Mutant Diffuse Midline Glioma to Irradiation.

Glucosylceramide Synthase Inhibitors Induce Ceramide Accumulation and Sensitize H3K27 Mutant Diffuse Midline Glioma to Irradiation.

Journal: International journal of molecular sciences
Published: April 22, 2023

Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression.

Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression.

Journal: Cancers
Published: November 30, 2022
Showing 1-12 of 61

Last Updated: 09/26/2026