Roland Frotschl
Kurt Georg Kiesinger Allee 3
Bonn, NW 53175, Germany
Bonn, NW 53175, Germany
Last Updated: 09/26/2026
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Found 41 publications
The in vitro alkaline comet assay with liver models as a complementary tool for genotoxicity assessment of N-nitrosamines.
Journal: Archives of toxicology
Published: March 26, 2026
Quantitative evaluation of genotoxicity data for risk assessment and regulatory decision-making: Time for a paradigm shift.
Journal: Environment international
Published: October 28, 2025
TGx-DDI (toxicogenomic DNA damage-inducing) biomarker validation: multi-site ring trial supporting regulatory use.
Journal: Toxicological sciences : an official journal of the Society of Toxicology
Published: October 01, 2025
Summary of Major Conclusions From the 8th International Workshop on Genotoxicity Testing (IWGT), Ottawa, Canada.
Journal: Environmental and molecular mutagenesis
Published: September 17, 2025
Evaluating the lifetime cumulative dose as a basis for carcinogenic potency of nitrosamines - a key tenet underpinning less-than-lifetime approaches for establishing acceptable intake limits.
Journal: Regulatory toxicology and pharmacology : RTP
Published: May 15, 2025
HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions.
Journal: Regulatory toxicology and pharmacology : RTP
Published: February 20, 2025
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines.
Journal: Environmental and molecular mutagenesis
Published: January 14, 2025
Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity.
Journal: Environmental and molecular mutagenesis
Published: September 17, 2024
Outcome of IWGT workshop on transcriptomic biomarkers for genotoxicity: Key considerations for bioinformatics.
Journal: Environmental and molecular mutagenesis
Published: September 05, 2024
Determining recommended acceptable intake limits for N-nitrosamine impurities in pharmaceuticals: Development and application of the Carcinogenic Potency Categorization Approach (CPCA).
Journal: Regulatory toxicology and pharmacology : RTP
Published: April 22, 2024
In vivo alkaline comet assay: Statistical considerations on historical negative and positive control data.
Journal: Regulatory toxicology and pharmacology : RTP
Published: November 01, 2023
Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology.
Journal: Mutagenesis
Published: June 10, 2023
Last Updated: 09/26/2026