Roland Kanaar

Rotterdam, ZH, Netherlands

Last Updated: 09/26/2026

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Found 97 publications

Differential roles of DNA double strand break repair pathways in response to X-ray, proton, and alpha-particle irradiation.

Differential roles of DNA double strand break repair pathways in response to X-ray, proton, and alpha-particle irradiation.

Journal: International journal of radiation biology

Published: December 04, 2025

FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments.

FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments.

Journal: Science (New York, N.Y.)

Published: October 30, 2025

Motion based ex vivo (MOTEX) culture of breast tumor slices sustains microenvironment composition.

Motion based ex vivo (MOTEX) culture of breast tumor slices sustains microenvironment composition.

Journal: Neoplasia (New York, N.Y.)

Published: July 14, 2025

A Reporter Platform to Study Therapy-Induced Senescence in Live Cancer Cells.

A Reporter Platform to Study Therapy-Induced Senescence in Live Cancer Cells.

Journal: Small methods

Published: June 27, 2025

Tetramerization of the DNA mismatch repair protein MutS enhances daughter strand incision preferentially in the vicinity of replication errors.

Tetramerization of the DNA mismatch repair protein MutS enhances daughter strand incision preferentially in the vicinity of replication errors.

Journal: The Journal of biological chemistry

Published: June 26, 2025

Curcumin Induces Homologous Recombination Deficiency by BRCA2 Degradation in Breast Cancer and Normal Cells.

Curcumin Induces Homologous Recombination Deficiency by BRCA2 Degradation in Breast Cancer and Normal Cells.

Journal: Cancers

Published: June 02, 2025

High-throughput spheroid-based assay for functional breast cancer precision medicine facilitated by deep learning.

High-throughput spheroid-based assay for functional breast cancer precision medicine facilitated by deep learning.

Journal: Communications medicine

Published: May 09, 2025

Contributions of DNA double strand break repair pathways to DNA crosslink repair.

Contributions of DNA double strand break repair pathways to DNA crosslink repair.

Journal: DNA repair

Published: February 11, 2025

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS-STING Pathway and Reverses Macrophage-Like VSMC Phenotypes in Progeroid DNA-Repair-Deficient Ercc1Δ /- Mice.

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS-STING Pathway and Reverses Macrophage-Like VSMC Phenotypes in Progeroid DNA-Repair-Deficient Ercc1Δ /- Mice.

Journal: Aging cell

Published: January 22, 2025

Enhanced radiosensitivity of head and neck cancer cells to proton therapy via hyperthermia-induced homologous recombination deficiency.

Enhanced radiosensitivity of head and neck cancer cells to proton therapy via hyperthermia-induced homologous recombination deficiency.

Journal: Clinical and translational radiation oncology

Published: September 24, 2024

Development and validation of a functional ex vivo paclitaxel and eribulin sensitivity assay for breast cancer, the REMIT assay.

Development and validation of a functional ex vivo paclitaxel and eribulin sensitivity assay for breast cancer, the REMIT assay.

Journal: NPJ breast cancer

Published: August 07, 2024

Synergistic Roles of Non-Homologous End Joining and Homologous Recombination in Repair of Ionizing Radiation-Induced DNA Double Strand Breaks in Mouse Embryonic Stem Cells.

Synergistic Roles of Non-Homologous End Joining and Homologous Recombination in Repair of Ionizing Radiation-Induced DNA Double Strand Breaks in Mouse Embryonic Stem Cells.

Journal: Cells

Published: July 24, 2024

Showing 1-12 of 97

Last Updated: 09/26/2026