Rolf W. Sparidans
Utrecht, UT, Netherlands
Last Updated: 09/26/2026
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Found 93 publications
Indoxyl sulfate as a potential tubular function marker across kidney disease models.
Journal: American journal of physiology. Renal physiology
Published: June 11, 2025
Lung Acetate Levels Decline in Correlation With Increased Type 2 Allergic Markers in a House Dust Mite Allergic Mouse Model.
Journal: Clinical and translational allergy
Published: May 07, 2025
Protein-bound uremic toxin clearance as biomarker of kidney tubular function in diabetic kidney disease.
Journal: Scientific reports
Published: March 16, 2025
Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.
Journal: Molecular pharmaceutics
Published: September 23, 2024
ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: February 28, 2024
Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: January 27, 2024
The ABCB1 and ABCG2 efflux transporters limit brain disposition of the SYK inhibitors entospletinib and lanraplenib.
Journal: Toxicology and applied pharmacology
Published: December 23, 2023
Cerebrospinal Fluid Concentration of the RET Inhibitor Pralsetinib: A Case Report.
Journal: Case reports in oncology
Published: October 17, 2023
Development and validation of an LC-MS/MS method for the quantification of KRASG12C inhibitor opnurasib in several mouse matrices and its application in a pharmacokinetic mouse study.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Published: September 25, 2023
Validated LC-MS/MS method for simultaneous quantification of KRASG12C inhibitor sotorasib and its major circulating metabolite (M24) in mouse matrices and its application in a mouse pharmacokinetic study.
Journal: Journal of pharmaceutical and biomedical analysis
Published: April 24, 2023
Pharmacokinetics of the KRASG12C inhibitor adagrasib is limited by CYP3A and ABCB1, and influenced by binding to mouse plasma carboxylesterase 1c.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: March 29, 2023
Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs.
Journal: Pharmacological research
Published: January 17, 2023
Last Updated: 09/26/2026