Romain Silly-De

Lausanne, VD, Switzerland

Last Updated: 09/26/2026

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Found 13 publications

High-titer modular retroviral vectors enabled by an antisense cassette design preventing dsRNA formation during virus production.

High-titer modular retroviral vectors enabled by an antisense cassette design preventing dsRNA formation during virus production.

Journal: Molecular therapy. Advances
Published: January 05, 2026

Gamma-retrovirus design for efficacious microRNA-mediated gene knock-down and protein co-expression without compromising titers.

Gamma-retrovirus design for efficacious microRNA-mediated gene knock-down and protein co-expression without compromising titers.

Journal: NAR molecular medicine
Published: April 10, 2025

Acidity suppresses CD8 + T-cell function by perturbing IL-2, mTORC1, and c-Myc signaling.

Acidity suppresses CD8 + T-cell function by perturbing IL-2, mTORC1, and c-Myc signaling.

Journal: The EMBO journal
Published: February 26, 2024

Enforcing GLUT3 expression in CD8+ T cells improves fitness and tumor control by promoting glucose uptake and energy storage.

Enforcing GLUT3 expression in CD8+ T cells improves fitness and tumor control by promoting glucose uptake and energy storage.

Journal: Frontiers in immunology
Published: June 23, 2022

A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor.

A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor.

Journal: Nature biomedical engineering
Published: March 15, 2022

Anti-Ly6G binding and trafficking mediate positive neutrophil selection to unleash the anti-tumor efficacy of radiation therapy.

Anti-Ly6G binding and trafficking mediate positive neutrophil selection to unleash the anti-tumor efficacy of radiation therapy.

Journal: Oncoimmunology
Published: February 25, 2021

Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.

Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.

Journal: Cancer science
Published: June 26, 2020

Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the Fuel.

Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the Fuel.

Journal: Frontiers in immunology
Published: January 10, 2017

Hypoxia and antitumor CD8+ T cells: An incompatible alliance?

Hypoxia and antitumor CD8+ T cells: An incompatible alliance?

Journal: Oncoimmunology
Published: July 20, 2016

Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing.

Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing.

Journal: PloS one
Published: April 14, 2016

Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells.

Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells.

Journal: European journal of immunology
Published: October 23, 2014

Myeloid-derived suppressor cells: mechanisms of action and recent advances in their role in transplant tolerance.

Myeloid-derived suppressor cells: mechanisms of action and recent advances in their role in transplant tolerance.

Journal: Frontiers in immunology
Published: March 27, 2012
Showing 1-12 of 13

Last Updated: 09/26/2026