Roman Istomine

Montreal, QC H4A3J1, Canada

Last Updated: 09/26/2026

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Found 14 publications

Anti-PD-1 amplifies costimulation in melanoma-infiltrating Th1-like Foxp3+ regulatory T cells to alleviate local immunosuppression.

Anti-PD-1 amplifies costimulation in melanoma-infiltrating Th1-like Foxp3+ regulatory T cells to alleviate local immunosuppression.

Journal: Journal for immunotherapy of cancer
Published: November 14, 2024

IL-18 is required for the TH1-adaptation of TREG cells and the selective suppression of TH17 responses in acute and chronic infections.

IL-18 is required for the TH1-adaptation of TREG cells and the selective suppression of TH17 responses in acute and chronic infections.

Journal: Mucosal immunology
Published: December 15, 2022

The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism.

The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism.

Journal: iScience
Published: July 29, 2022

A Hemagglutinin 1 Carrying Plant-Based Virus-like Particle Vaccine Generates an Efficacious Cellular Response by Exploiting IL-1 Signaling in Both Adult and Aged Mice.

A Hemagglutinin 1 Carrying Plant-Based Virus-like Particle Vaccine Generates an Efficacious Cellular Response by Exploiting IL-1 Signaling in Both Adult and Aged Mice.

Journal: ImmunoHorizons
Published: May 12, 2022

ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation.

ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation.

Journal: Journal of immunology (Baltimore, Md. : 1950)
Published: September 13, 2021

Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes.

Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes.

Journal: Diabetes
Published: August 23, 2019

Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells.

Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells.

Journal: Cell reports
Published: July 30, 2019

The Deubiquitinating Enzyme Ubiquitin-Specific Peptidase 11 Potentiates TGF-β Signaling in CD4+ T Cells to Facilitate Foxp3+ Regulatory T and TH17 Cell Differentiation.

The Deubiquitinating Enzyme Ubiquitin-Specific Peptidase 11 Potentiates TGF-β Signaling in CD4+ T Cells to Facilitate Foxp3+ Regulatory T and TH17 Cell Differentiation.

Journal: Journal of immunology (Baltimore, Md. : 1950)
Published: December 31, 2018

Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases.

Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases.

Journal: Nature communications
Published: August 06, 2018

The alarmins IL-1 and IL-33 differentially regulate the functional specialisation of Foxp3+ regulatory T cells during mucosal inflammation.

The alarmins IL-1 and IL-33 differentially regulate the functional specialisation of Foxp3+ regulatory T cells during mucosal inflammation.

Journal: Mucosal immunology
Published: July 25, 2018

Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.

Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 22, 2018

KLRG1 expression identifies short-lived Foxp3+ Treg effector cells with functional plasticity in islets of NOD mice.

KLRG1 expression identifies short-lived Foxp3+ Treg effector cells with functional plasticity in islets of NOD mice.

Journal: Autoimmunity
Published: August 30, 2017
Showing 1-12 of 14

Last Updated: 09/26/2026