Rosa Alen

Madrid, MD, Spain

Last Updated: 09/26/2026

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Found 9 publications

MTFP1 preserves β-cell cristae structure and bioenergetics to ensure insulin release and glucose homeostasis.

MTFP1 preserves β-cell cristae structure and bioenergetics to ensure insulin release and glucose homeostasis.

Journal: bioRxiv : the preprint server for biology

Published: February 06, 2026

Effect of lipotoxic hepatocyte-derived extracellular vesicles in pancreas inflammation: essential role of macrophage TLR4 in beta cell functionality.

Effect of lipotoxic hepatocyte-derived extracellular vesicles in pancreas inflammation: essential role of macrophage TLR4 in beta cell functionality.

Journal: Diabetologia

Published: January 07, 2025

Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition.

Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition.

Journal: Redox biology

Published: April 21, 2023

Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance.

Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance.

Journal: JHEP reports : innovation in hepatology

Published: July 07, 2022

Attenuation of Olanzapine-Induced Endoplasmic Reticulum Stress Improves Insulin Secretion in Pancreatic Beta Cells.

Attenuation of Olanzapine-Induced Endoplasmic Reticulum Stress Improves Insulin Secretion in Pancreatic Beta Cells.

Journal: Metabolites

Published: April 10, 2022

The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.

The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.

Journal: Nature communications

Published: April 07, 2021

Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress.

Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress.

Journal: Aging

Published: September 22, 2020

Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis.

Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis.

Journal: Frontiers in medicine

Published: April 27, 2020

Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.

Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice.

Journal: Molecular metabolism

Published: October 21, 2019

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Last Updated: 09/26/2026