Rosemary B. Cornell

Burnaby, BC V5A1S6, Canada

Last Updated: 09/26/2026

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Found 17 publications

Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets.

Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets.

Journal: Molecular biology of the cell

Published: March 19, 2020

Membrane Lipids Assist Catalysis by CTP: Phosphocholine Cytidylyltransferase.

Membrane Lipids Assist Catalysis by CTP: Phosphocholine Cytidylyltransferase.

Journal: Journal of molecular biology

Published: December 17, 2019

Interdomain communication in the phosphatidylcholine regulatory enzyme, CCTα, relies on a modular αE helix.

Interdomain communication in the phosphatidylcholine regulatory enzyme, CCTα, relies on a modular αE helix.

Journal: The Journal of biological chemistry

Published: June 18, 2019

Remodeling of the interdomain allosteric linker upon membrane binding of CCTα pulls its active site close to the membrane surface.

Remodeling of the interdomain allosteric linker upon membrane binding of CCTα pulls its active site close to the membrane surface.

Journal: The Journal of biological chemistry

Published: June 18, 2019

Disease-linked mutations in the phosphatidylcholine regulatory enzyme CCTα impair enzymatic activity and fold stability.

Disease-linked mutations in the phosphatidylcholine regulatory enzyme CCTα impair enzymatic activity and fold stability.

Journal: The Journal of biological chemistry

Published: October 26, 2018

CCTα Commands Phospholipid Homeostasis from the Nucleus.

CCTα Commands Phospholipid Homeostasis from the Nucleus.

Journal: Developmental cell

Published: May 23, 2018

An auto-inhibitory helix in CTP:phosphocholine cytidylyltransferase hijacks the catalytic residue and constrains a pliable, domain-bridging helix pair.

An auto-inhibitory helix in CTP:phosphocholine cytidylyltransferase hijacks the catalytic residue and constrains a pliable, domain-bridging helix pair.

Journal: The Journal of biological chemistry

Published: January 23, 2018

Membrane lipid compositional sensing by the inducible amphipathic helix of CCT.

Membrane lipid compositional sensing by the inducible amphipathic helix of CCT.

Journal: Biochimica et biophysica acta

Published: November 09, 2015

CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis.

CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis.

Journal: Progress in lipid research

Published: May 07, 2015

Isoform-specific and protein kinase C-mediated regulation of CTP:phosphoethanolamine cytidylyltransferase phosphorylation.

Isoform-specific and protein kinase C-mediated regulation of CTP:phosphoethanolamine cytidylyltransferase phosphorylation.

Journal: The Journal of biological chemistry

Published: February 13, 2014

The curvature sensitivity of a membrane-binding amphipathic helix can be modulated by the charge on a flanking region.

The curvature sensitivity of a membrane-binding amphipathic helix can be modulated by the charge on a flanking region.

Journal: Biochemistry

Published: January 09, 2014

Structural basis for autoinhibition of CTP:phosphocholine cytidylyltransferase (CCT), the regulatory enzyme in phosphatidylcholine synthesis, by its membrane-binding amphipathic helix.

Structural basis for autoinhibition of CTP:phosphocholine cytidylyltransferase (CCT), the regulatory enzyme in phosphatidylcholine synthesis, by its membrane-binding amphipathic helix.

Journal: The Journal of biological chemistry

Published: November 27, 2013

Showing 1-12 of 17

Last Updated: 09/26/2026