Rosie Goddard-Upstill

Glasgow, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 13 publications

Cancer-associated fibroblasts regulate DNA repair in pancreatic cancer through NDRG1-mediated R-loop processing.

Cancer-associated fibroblasts regulate DNA repair in pancreatic cancer through NDRG1-mediated R-loop processing.

Journal: Nature cell biology
Published: December 12, 2025

A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance.

A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance.

Journal: bioRxiv : the preprint server for biology
Published: February 03, 2025

Clonal evolutionary analysis reveals patterns of malignant transformation of Intraductal Papillary Mucinous Neoplasms of the pancreas.

Clonal evolutionary analysis reveals patterns of malignant transformation of Intraductal Papillary Mucinous Neoplasms of the pancreas.

Journal: Nature communications
Published: January 05, 2025

Sequential ATR and PARP inhibition overcomes acquired DNA damaging agent resistance in pancreatic ductal adenocarcinoma.

Sequential ATR and PARP inhibition overcomes acquired DNA damaging agent resistance in pancreatic ductal adenocarcinoma.

Journal: British journal of cancer
Published: September 17, 2024

Integrating metabolic profiling of pancreatic juice with transcriptomic analysis of pancreatic cancer tissue identifies distinct clinical subgroups.

Integrating metabolic profiling of pancreatic juice with transcriptomic analysis of pancreatic cancer tissue identifies distinct clinical subgroups.

Journal: Frontiers in oncology
Published: March 23, 2024

Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy.

Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy.

Journal: Gut
Published: July 26, 2023

The Impact of Molecular Subtyping on Pathological Staging of Pancreatic Cancer.

The Impact of Molecular Subtyping on Pathological Staging of Pancreatic Cancer.

Journal: Annals of surgery
Published: February 06, 2023

FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer.

FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer.

Journal: Gut
Published: May 24, 2022

Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence.

Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence.

Journal: Gastroenterology
Published: May 07, 2021

Using Chromatin Accessibility to Delineate Therapeutic Subtypes in Pancreatic Cancer Patient-Derived Cell Lines.

Using Chromatin Accessibility to Delineate Therapeutic Subtypes in Pancreatic Cancer Patient-Derived Cell Lines.

Journal: STAR protocols
Published: October 28, 2020

Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage.

Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage.

Journal: Nature communications
Published: October 06, 2020

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer.

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer.

Journal: Gastroenterology
Published: August 08, 2019
Showing 1-12 of 13

Last Updated: 09/26/2026