Ross C. Overman

Norwich Research Park
Norwich, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 22 publications

Affimer reagents enable targeted delivery of therapeutic agents and RNA via virus-like particles.

Affimer reagents enable targeted delivery of therapeutic agents and RNA via virus-like particles.

Journal: iScience
Published: November 17, 2023

Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy.

Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy.

Journal: Journal of medicinal chemistry
Published: March 08, 2021

Engineered Cas9 extracellular vesicles as a novel gene editing tool.

Engineered Cas9 extracellular vesicles as a novel gene editing tool.

Journal: Journal of extracellular vesicles
Published: February 23, 2021

A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding.

A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding.

Journal: The Biochemical journal
Published: September 11, 2020

Structural and binding characterization of the LacdiNAc-specific adhesin (LabA; HopD) exodomain from Helicobacter pylori.

Structural and binding characterization of the LacdiNAc-specific adhesin (LabA; HopD) exodomain from Helicobacter pylori.

Journal: Current research in structural biology
Published: August 24, 2020

Plant-made dengue virus-like particles produced by co-expression of structural and non-structural proteins induce a humoral immune response in mice.

Plant-made dengue virus-like particles produced by co-expression of structural and non-structural proteins induce a humoral immune response in mice.

Journal: Plant biotechnology journal
Published: May 05, 2020

Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo.

Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo.

Journal: Nanomedicine (London, England)
Published: November 15, 2019

Discovery and pharmacological characterization of AZD3229, a potent KIT/PDGFRα inhibitor for treatment of gastrointestinal stromal tumors.

Discovery and pharmacological characterization of AZD3229, a potent KIT/PDGFRα inhibitor for treatment of gastrointestinal stromal tumors.

Journal: Science translational medicine
Published: August 24, 2019

Introduction of a C-terminal hexa-lysine tag increases thermal stability of the LacDiNac binding adhesin (LabA) exodomain from Helicobacter pylori.

Introduction of a C-terminal hexa-lysine tag increases thermal stability of the LacDiNac binding adhesin (LabA) exodomain from Helicobacter pylori.

Journal: Protein expression and purification
Published: May 15, 2019

The structure of human GCN2 reveals a parallel, back-to-back kinase dimer with a plastic DFG activation loop motif.

The structure of human GCN2 reveals a parallel, back-to-back kinase dimer with a plastic DFG activation loop motif.

Journal: The Biochemical journal
Published: March 11, 2019

KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.

KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.

Journal: Nature communications
Published: October 16, 2018

Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.

Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.

Journal: Journal of medicinal chemistry
Published: September 12, 2018
Showing 1-12 of 22

Last Updated: 09/26/2026